Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

1,679 questions · 1,720 findings · 335 reviews · Headline outcomes only

No studies found 192 · 11.2%GRADE not reported 75 · 4.4%Very low 526 · 30.6%Low 504 · 29.3%Moderate 305 · 17.7%High 118 · 6.9%

Chemotherapy plus involved‐field radiation vs same chemotherapy plus extended‐field radiation

Progression/relapse · Patients with untreated Hodgkin lymphoma (early stages)

Chemotherapy plus involved‐field radiation showed no clear difference in progression/relapse compared with same chemotherapy plus extended‐field radiation (high certainty).

1 finding from 1 review

Chemotherapy plus lower‐dose radiation vs same chemotherapy plus higher‐dose radiation

Secondary malignant neoplasms · Patients with untreated Hodgkin lymphoma (early stages)

Chemotherapy plus lower‐dose radiation showed no clear difference in secondary malignant neoplasms compared with same chemotherapy plus higher‐dose radiation (low certainty).

1 finding from 1 review

Chemotherapy plus lower‐dose radiation vs same chemotherapy plus higher‐dose radiation

Death · Patients with untreated Hodgkin lymphoma (early stages)

Chemotherapy plus lower‐dose radiation showed no clear difference in death compared with same chemotherapy plus higher‐dose radiation (high certainty).

1 finding from 1 review

Chemotherapy plus lower‐dose radiation vs same chemotherapy plus higher‐dose radiation

Progression/relapse · Patients with untreated Hodgkin lymphoma (early stages)

Chemotherapy plus lower‐dose radiation showed no clear difference in progression/relapse compared with same chemotherapy plus higher‐dose radiation (high certainty).

1 finding from 1 review

Intervention not reported

Late embryo transfer ‐ GM501 (specific) versus Sydney IVF (other) · Women in assisted reproductive technology cycles (ART) receiving human pre‐implantation embryos in either early (cleavage stage transfer)…

It is very uncertain whether the intervention changes late embryo transfer ‐ GM501 (specific) versus Sydney IVF (other) (very low certainty).

1 finding from 1 review

Intervention not reported

Late embryo transfer ‐ G2 (specific) versus Universal IVF (other) · Women in assisted reproductive technology cycles (ART) receiving human pre‐implantation embryos in either early (cleavage stage transfer)…

It is very uncertain whether the intervention changes late embryo transfer ‐ G2 (specific) versus Universal IVF (other) (very low certainty).

1 finding from 1 review

Intervention not reported

Late embryo transfer ‐ ECM/Multiblast (specific) versus Global (other) · Women in assisted reproductive technology cycles (ART) receiving human pre‐implantation embryos in either early (cleavage stage transfer)…

It is very uncertain whether the intervention changes late embryo transfer ‐ ECM/Multiblast (specific) versus Global (other) (very low certainty).

1 finding from 1 review

Intervention not reported

Ascitis · Patients with dengue infection at an early stage

It is very uncertain whether the intervention changes ascitis (very low certainty).

1 finding from 1 review

Intervention not reported

ICU admission · Patients with dengue infection at an early stage

It is very uncertain whether the intervention changes ICU admission (very low certainty).

1 finding from 1 review

Intervention not reported

Death · Patients with dengue infection at an early stage
1 finding from 1 review

Intervention not reported

Severe dengue: shock · Patients with dengue infection at an early stage

It is very uncertain whether the intervention changes severe dengue: shock (very low certainty).

1 finding from 1 review

Intervention not reported

Severe dengue: severe bleeding · Patients with dengue infection at an early stage

It is very uncertain whether the intervention changes severe dengue: severe bleeding (very low certainty).

1 finding from 1 review

Intervention not reported

Severe thrombocytopaenia11 · Patients with dengue infection at an early stage

It is very uncertain whether the intervention changes severe thrombocytopaenia11 (very low certainty).

1 finding from 1 review