Cochrane · systematic review · CD003046
Radiofrequency (thermal) ablation versus no intervention or other interventions for hepatocellular carcinoma
Weis, S, Franke, A, Mössner, J, et al. · Cochrane Database of Systematic Reviews · 2013 · Cochrane Library
Hepato-BiliaryAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
12
current version
GRADE rated
12
No studies
0
Included studies
NR
No studies 0 · 0%Ungraded 0 · 0%Very low 0 · 0%Low 1 · 8.3%Moderate 9 · 75%High 2 · 16.7%
Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.
Questions and results
Hepatic resection compared with radiofrequency ablation
Population: 578 patients with early HCC
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Overall survival Hepatic resection vs radiofrequency ablation | no estimate extracted | 3 studies · 578 participants | Moderate |
2‐year survival‐ Hepatic resection vs radiofrequency ablation | no estimate extracted | 3 studies · 578 participants | Moderate |
Event‐free survival Hepatic resection vs radiofrequency ablation | no estimate extracted | 3 studies · 578 participants | Moderate |
Local progression Hepatic resection vs radiofrequency ablation | no estimate extracted | 1 study · 168 participants | Low |
Rate of complications Hepatic resection vs radiofrequency ablation | no estimate extracted | 3 studies · 578 participants | High |
Length of hospital stay (days) Hepatic resection vs radiofrequency ablation | no estimate extracted | 3 studies · 578 participants | High |
Percutaneous ethanol injection compared with radiofrequency ablation for early hepatocellular carcinoma
Population: 1088 patients with early HCC
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Overall survival Percutaneous ethanol injection vs radiofrequency ablation | no estimate extracted | 6 studies · 1088 participants | Moderate |
2‐year survival Percutaneous ethanol injection vs radiofrequency ablation | no estimate extracted | 4 studies · 715 participants | Moderate |
Event‐free survival Percutaneous ethanol injection vs radiofrequency ablation | no estimate extracted | 5 studies · 949 participants | Moderate |
Local progression Percutaneous ethanol injection vs radiofrequency ablation | no estimate extracted | 4 studies · 678 participants | Moderate |
Rate of complications Percutaneous ethanol injection vs radiofrequency ablation | no estimate extracted | 6 studies · 1088 participants | Moderate |
Length of hospital stay Percutaneous ethanol injection vs radiofrequency ablation | no estimate extracted | 3 studies · 576 participants | Moderate |