Cochrane · systematic review · CD003488
Corticosteroids for dengue infection
Zhang, F, Kramer, CV · Cochrane Database of Systematic Reviews · 2014 · Cochrane Library
Infectious DiseasesAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
11
current version
GRADE rated
11
No studies
0
Included studies
NR
No studies 0 · 0%Ungraded 0 · 0%Very low 10 · 90.9%Low 1 · 9.1%Moderate 0 · 0%High 0 · 0%
Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.
Questions and results
Corticosteroid for dengue‐related shock
Population: Patients with dengue‐related shock
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Death | RR 0.68 [0.42, 1.11] | 4 studies · 284 participants | Very low Downgraded: risk of bias, imprecision, inconsistency, indirectness |
Need for blood transfusion | RR 1.08 [0.52, 2.24] | 2 studies · 89 participants | Very low Downgraded: risk of bias, imprecision, inconsistency, indirectness |
Pulmonary haemorrhage | RR 0.97 [0.06, 14.82] | 1 study · 63 participants | Very low Downgraded: risk of bias, imprecision, indirectness |
Convulsions | RR 6.79 [0.36, 126.24] | 1 study · 63 participants | Very low Downgraded: risk of bias, imprecision, indirectness |
Days in hospital | no estimate extracted | 1 study · 63 participants | Very low Downgraded: risk of bias, imprecision, indirectness |
Corticosteroid for dengue at an early stage
Population: Patients with dengue infection at an early stage
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Death | no estimate extracted | 4 studies · 664 participants | Low Downgraded: risk of bias |
Severe dengue: shock | RR 1.3 [0.48, 3.51] | 2 studies · 286 participants | Very low Downgraded: risk of bias, imprecision, inconsistency, indirectness |
Severe dengue: severe bleeding | RR 1.51 [0.24, 9.43] | 2 studies · 425 participants | Very low Downgraded: risk of bias, imprecision, inconsistency, indirectness |
Severe thrombocytopaenia11 | RR 1.51 [0.31, 7.28] | 1 study · 225 participants | Very low Downgraded: risk of bias, imprecision, inconsistency, indirectness |
Ascitis | RR 0.12 [0.01, 2.13] | 1 study · 178 participants | Very low Downgraded: risk of bias, imprecision, inconsistency, indirectness |
ICU admission | RR 0.88 [0.38, 1.99] | 2 studies · 286 participants | Very low Downgraded: risk of bias, imprecision, inconsistency, indirectness |