Intervention not reported
Participants with at least 1 adverse event (all diclofenac potassium doses, 25 mg to 100 mg) · Adults with acute pain
The intervention showed no clear difference in participants with at least 1 adverse event (all diclofenac potassium… (moderate certainty).
1 finding from 1 review
Intervention not reported
Participants with a serious adverse event (whole data set) · Adults with acute pain
1 finding from 1 review
Intervention not reported
At least 50% of maximum pain relief over 4 to 6 h · adults with moderate or severe acute postoperative pain
The intervention leads to higher at least 50% of maximum pain relief over 4 to 6 h (high certainty).
1 finding from 1 review
RR 4.1 [2.8, 5.9]
Studies not reported
High
Intervention not reported
Participants with at least 1 adverse event · adults with moderate or severe acute postoperative pain
The intervention showed no clear difference in participants with at least 1 adverse event (moderate certainty).
1 finding from 1 review
RR 1.2 [0.84, 1.7]
Studies not reported
Moderate
Intervention not reported
Participants with a serious adverse event · adults with moderate or severe acute postoperative pain
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Intervention not reported
Deaths · adults with moderate or severe acute postoperative pain
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
All‐cause mortality · patients with endotracheal intubation in critically ill patients
Etomidate showed no clear difference in mortality compared with all other induction agents (moderate certainty).
1 finding from 1 review
ACTH stimulation test ACTH stimulation test is considered positive if the change in serum cortisol level was less than 9 μg/dL (248 nmol/L) after the administration of 250 μg of cosyntropin · patients with endotracheal intubation in critically ill patients
Etomidate probably leads to higher ACTH stimulation test ACTH stimulation test is considered positive… compared with all other induction agents (moderate certainty).
1 finding from 1 review
Random serum cortisol levels (μg/dL) after receiving intervention · patients with endotracheal intubation in critically ill patients
1 finding from 1 review
Organ system dysfunction (during admission) · patients with endotracheal intubation in critically ill patients
1 finding from 1 review
Duration of ICU stay · patients with endotracheal intubation in critically ill patients
1 finding from 1 review
Length of hospital stay · patients with endotracheal intubation in critically ill patients
1 finding from 1 review
Duration of mechanical ventilation · patients with endotracheal intubation in critically ill patients
1 finding from 1 review
Intervention not reported
At least 50% of maximum pain relief over 4 to 6 h · Adults with acute pain
The intervention probably leads to higher at least 50% of maximum pain relief over 4 to 6 h (moderate certainty).
1 finding from 1 review
Intervention not reported
Participants remedicating within 8 hours · Adults with acute pain
The intervention probably leads to lower participants remedicating within 8 hours (moderate certainty).
1 finding from 1 review
Intervention not reported
Participants with at least 1 adverse event · Adults with acute pain
The intervention showed no clear difference in participants with at least 1 adverse event (low certainty).
1 finding from 1 review
Intervention not reported
Participants with a serious adverse event · Adults with acute pain
1 finding from 1 review
Intervention not reported
At least 50% of maximum pain relief over 4 to 6 hours · adults with moderate or severe acute postoperative pain
The intervention leads to higher at least 50% of maximum pain relief over 4 to 6 hours (high certainty).
1 finding from 1 review
RR 5.6 [4, 7.8]
Studies not reported
High
Intervention not reported
Participants with at least 1 adverse event · adults with moderate or severe acute postoperative pain
The intervention showed no clear difference in participants with at least 1 adverse event (moderate certainty).
1 finding from 1 review
RR 0.93 [0.74, 1.2]
Studies not reported
Moderate
Intervention not reported
Participants with a serious adverse event · adults with moderate or severe acute postoperative pain
1 finding from 1 review
no estimate extracted
Studies not reported
Low