Cochrane · systematic review · CD004768
Single dose oral diclofenac for acute postoperative pain in adults
Derry, S, Wiffen, PJ, Moore, RA · Cochrane Database of Systematic Reviews · 2015 · Cochrane Library
Pain, Palliative and Supportive CareAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
4
current version
GRADE rated
4
No studies
0
Included studies
NR
No studies 0 · 0%Ungraded 0 · 0%Very low 0 · 0%Low 1 · 25%Moderate 1 · 25%High 2 · 50%
Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.
Questions and results
Comparison
Population: Adults with acute pain
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
At least 50% of maximum pain relief over 4 to 6 hours | RR 3.7 [2.9, 4.7] | 7 studies · 757 participants | High |
Participants remedicating within 8 hours | RR 0.5 [0.45, 0.6] | 7 studies · 757 participants | High |
Participants with at least 1 adverse event (all diclofenac potassium doses, 25 mg to 100 mg) | RR 1 [0.7, 1.6] | 7 studies · 1090 participants | Moderate |
Participants with a serious adverse event (whole data set) | no estimate extracted | 18 studies · 2830 participants | Low |