Findings

What do systematic reviews say?

Refine by population, intervention, comparison or outcome
More filters
Evidence found and GRADE certainty

668 questions · 685 findings · 68 reviews · Headline outcomes only

No studies found 181 · 26.4%GRADE not reported 16 · 2.3%Very low 151 · 22%Low 211 · 30.8%Moderate 98 · 14.3%High 28 · 4.1%

Summary of findings: urate oxidase vs allopurinol

Organ system failure ‐ Renal insufficiency leading to replacement therapy · children with haematological malignancy at risk of tumour lysis syndrome

It is very uncertain whether summary of findings: urate oxidase changes renal failure requiring renal replacement therapy ( compared with allopurinol (very low certainty).

1 finding from 1 review

Statins vs placebo

Freedom from valve replacement · patients with aortic valve stenosis

Statin showed no clear difference in freedom from valve replacement compared with placebo (moderate certainty).

1 finding from 1 review

Intervention not reported

Number of smokers receiving nicotine gum/replacement therapy self‐report · Smokers treated by health professionals

The intervention showed no clear difference in number of smokers receiving nicotine gum/replacement therapy… (low certainty).

1 finding from 1 review

Longer vs shorter duration of combination nicotine replacement therapy

Smoking cessation ‐ 16 weeks versus 8 weeks · people who smoke

It is very uncertain whether longer changes smoking cessation ‐ 16 weeks versus 8 weeks compared with shorter duration of combination nicotine replacement therapy (very low certainty).

1 finding from 1 review