Any adverse effect related to aPDT · Adults (> 18 years) with a clinical diagnosis of periodontitis, receiving active (non-surgical anti-infective) treatment
1 finding from 1 review
Risk with control: 23 studies reported that no adverse effects of aPDT were observed. Number of participants (studies): 639 (24 studies). Certainty: Moderate. (24 studies reported adverse effects, with all studies…
24 studies · 639 participants
Moderate
Subjective evaluation (SAQ General) – PSSE plus bracing vs bracing alone · adolescents with idiopathic scoliosis
1 finding from 1 review
Effect on later sexual function · symptomatic or early postmenopausal women1.
1 finding from 1 review
5c. Moderate‐to‐severe neurodevelopmental disability or intellectual impairment after 2 years of age – doxapram as an adjunct to methylxanthine compared to methylxanthine alone for the treatment of apnea · treatment of apnea
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
side‐effects ‐ side‐effects causing abandon · treatment of apnea
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
5c. Moderate‐to‐severe neurodevelopmental disability or intellectual impairment after 2 years of age – doxapram as an adjunct to methylxanthine compared to methylxanthine alone for the prevention of reintubation · prevention of reintubation
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
side‐effects ‐ side‐effects causing abandon · prevention of reintubation
It is very uncertain whether doxapram changes 6c. Side effects causing cessation of therapy – doxapram as an… compared with no treatment, placebo, methylxanthine (including theophylline,… (very low certainty).
1 finding from 1 review
Malaria infection incidence alone( · people living in malaria‐endemic areas
Topical repellents showed no clear difference in malaria infection incidence alone( compared with placebo or no treatment (low certainty).
1 finding from 1 review
Locoregional control · People receiving curative-intent treatment for oral cavity and oropharyngeal (squamous cell) cancer
Concomitant (concurrent) chemoradiotherapy led to lower locoregional control, concurrent chemoradiotherapy (platinum +… compared with radiotherapy alone (non-resectable tumours); GRADE not reported.
1 finding from 1 review
RR 0.75 [0.61, 0.93]
3 studies
GRADE not reported
Disease-free survival · People receiving curative-intent treatment for oral cavity and oropharyngeal (squamous cell) cancer
Concomitant (concurrent) chemoradiotherapy led to lower disease-free survival, concurrent chemoradiotherapy vs radiotherapy… compared with radiotherapy alone (non-resectable tumours); GRADE not reported.
1 finding from 1 review
HR 0.74 [0.67, 0.80]
13 studies
GRADE not reported
Overall survival, adjuvant concomitant chemoradiotherapy vs post-surgery radiotherapy alone · People receiving curative-intent treatment for oral cavity and oropharyngeal (squamous cell) cancer
Concomitant (concurrent) chemoradiotherapy probably leads to lower overall survival, concurrent chemoradiotherapy vs radiotherapy alone… compared with radiotherapy alone (non-resectable tumours) (moderate certainty).
1 finding from 1 review
Adverse effects: drowsiness (gabapentin alone) · People with primary burning mouth syndrome (BMS), that is, oral mucosal pain with no dental or medical cause for such symptoms
It is very uncertain whether anticonvulsants (gabapentin 300 mg/day) changes adverse effects: drowsiness (gabapentin alone) compared with placebo (very low certainty).
1 finding from 1 review
Intervention not reported
Number of patients with arrhythmia: Garlicin injection plus supportive therapy versus supportive therapy alone · patients with viral myocarditis
It is very uncertain whether the intervention changes number of patients with arrhythmia: Garlicin injection plus… (very low certainty).
1 finding from 1 review
Intervention not reported
Number of patients with arrhythmia: Danhong injection plus supportive therapy versus supportive therapy alone · patients with viral myocarditis
The intervention showed no clear difference in number of patients with arrhythmia: Danhong injection plus… (moderate certainty).
1 finding from 1 review
Intervention not reported
Number of patients with premature beat: Shortscape Fleabane injection plus supportive therapy versus supportive therapy alone · patients with viral myocarditis
The intervention showed no clear difference in number of patients with premature beat: Shortscape Fleabane… (low certainty).
1 finding from 1 review
Intervention not reported
Number of patients with premature beat: Astragaloside injection plus supportive therapy versus supportive therapy alone · patients with viral myocarditis
The intervention showed no clear difference in number of patients with premature beat: Astragaloside injection plus… (low certainty).
1 finding from 1 review
Intervention not reported
Number of patients with premature beat: Danhong injection plus supportive therapy versus supportive therapy alone · patients with viral myocarditis
The intervention probably leads to lower number of patients with premature beat: Danhong injection plus… (moderate certainty).
1 finding from 1 review
Intervention not reported
Number of patients with arrhythmia: Astragaloside injection plus supportive therapy versus supportive therapy alone · patients with viral myocarditis
It is very uncertain whether the intervention changes number of patients with arrhythmia: Astragaloside injection plus… (very low certainty).
1 finding from 1 review
Adverse effects of long‐term use of available topical agents · HIV‐infected adults (> 13 years of age, per CDC) with one or more painful intraoral aphthous ulcers
The review found no eligible studies for this question.
1 finding from 1 review
Adverse effects · Participants with a previous or current history of recurrent aphthous stomatitis (RAS), diagnosed on history and clinical examination;…
1 finding from 1 review