Gastrointestinal disorders not otherwise specified · any indication
Gastrointestinal adverse events in people taking macrolide antibiotics probably leads to higher gastrointestinal disorders not otherwise specified compared with placebo (moderate certainty).
1 finding from 1 review
Abdominal pain · any indication
Gastrointestinal adverse events in people taking macrolide antibiotics may leads to higher abdominal pain compared with placebo (low certainty).
1 finding from 1 review
Diarrhoea · any indication
Gastrointestinal adverse events in people taking macrolide antibiotics may leads to higher diarrhoea compared with placebo (low certainty).
1 finding from 1 review
Nausea · any indication
Gastrointestinal adverse events in people taking macrolide antibiotics probably leads to higher nausea compared with placebo (moderate certainty).
1 finding from 1 review
Vomiting · any indication
Gastrointestinal adverse events in people taking macrolide antibiotics probably leads to higher vomiting compared with placebo (moderate certainty).
1 finding from 1 review
AE: vitreous loss—any time point during or after surgery · patients undergoing cataract surgery
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Risk of any ocular infection within 1 month following corneal abrasion · children and adults with corneal abrasion
1 finding from 1 review
no estimate extracted
Studies not reported
Very low
Unscheduled visits 1 or more hospitalisations for any cause WMD of · children with asthma
School‐based ICS therapy showed no clear difference in unscheduled visits 1 or more hospitalisations for any cause WMD of compared with home therapy (low certainty).
1 finding from 1 review
All‐cause mortality during hospital stay · neonates with sepsis
Pentoxifylline with antibiotics (any dose or duration) may leads to lower all‐cause mortality during hospital stay compared with placebo or no intervention (low certainty).
1 finding from 1 review
Chronic lung disease · neonates with sepsis
It is very uncertain whether pentoxifylline with antibiotics (any dose or duration) changes chronic lung disease compared with placebo or no intervention (very low certainty).
1 finding from 1 review
Severe intraventricular haemorrhage · neonates with sepsis
It is very uncertain whether pentoxifylline with antibiotics (any dose or duration) changes severe intraventricular haemorrhage compared with placebo or no intervention (very low certainty).
1 finding from 1 review
Periventricular leukomalacia · neonates with sepsis
It is very uncertain whether pentoxifylline with antibiotics (any dose or duration) changes periventricular leukomalacia compared with placebo or no intervention (very low certainty).
1 finding from 1 review
Length of hospital stay · neonates with sepsis
Pentoxifylline with antibiotics (any dose or duration) showed no clear difference in length of hospital stay (LOS) in days compared with placebo or no intervention (low certainty).
1 finding from 1 review
Satisfaction with treatment: from the perspective of consumer, family and informal carers or professionals/carers at any point during the acute management stage · psychosis‐induced aggression or agitation
1 finding from 1 review
Dental caries in children · Adolescents (12-18 years) without background systemic disease
In a subgroup analysis, probiotics reduced the number of caries in adolescents (MD -0.60, 95%CI -0.92 to -0.28; p-interaction=0.02); not GRADE-rated.
1 finding from 1 review
Gingival index (GI) · Children and/or adolescents (<18 years) without background systemic disease
Probiotics probably make little to no difference to the gingival index versus control (MD 0.04, 95%CI -0.18 to 0.27; low certainty).
1 finding from 1 review
Lactobacillus count (CFU/mL) · Children and/or adolescents (<18 years) without background systemic disease
Probiotics may make little to no difference to Lactobacillus count versus control (MD -0.78 CFU/mL, 95%CI -1.65 to 0.09; very low certainty).
1 finding from 1 review
Salivary pH · Children and/or adolescents (<18 years) without background systemic disease
Probiotics may make little to no difference to salivary pH versus control (MD -0.12 pH units, 95%CI -0.72 to 0.48; very low certainty).
1 finding from 1 review
Dental caries in children · Children and/or adolescents (<18 years) without background systemic disease
Probiotics probably make little to no difference to the number of dental caries versus control (MD -0.24 carious pieces, 95%CI -0.72 to 0.23; low certainty).
1 finding from 1 review
Streptococcus mutans count · Children and/or adolescents (<18 years) without background systemic disease
Probiotics probably reduce Streptococcus mutans count versus control (MD -0.40 CFU/mL, 95%CI -0.57 to -0.24; moderate certainty).
1 finding from 1 review