Question · asked by 1 review

Gastrointestinal adverse events in people taking macrolide antibiotics vs placebo: Nausea

Gastrointestinal adverse events in people taking macrolide antibiotics probably leads to higher nausea compared with placebo (moderate certainty).

What each review found

Include earlier review versions
FindingEffectStudiesGRADE certainty
Gastrointestinal adverse events in people taking macrolide antibiotics vs placebo
Nausea · any indication
Gastrointestinal adverse events in people taking macrolide antibiotics probably leads to higher nausea compared with placebo (moderate certainty).
Adverse events in people taking macrolide antibiotics versus placebo for any indication (2019) · Cochrane Headline outcomes only
OR 1.61 [1.37, 1.9]28 studies · 14983 participantsModerate

Findings are shown side by side, never pooled across reviews.

The reviews

ReviewSearched up toIncluded studiesAMSTAR 2
Adverse events in people taking macrolide antibiotics versus placebo for any indication
2019 · Cochrane Headline outcomes only
Not reportedlist not extracted yetNot assessed

Studies behind the findings

None of these reviews ties its included studies to this outcome in the data here. Cochrane reviews and reviews with headline outcomes only do not list their studies yet.

How reviews are matched to this question

Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.