Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

288 questions · 290 findings · 74 reviews · Headline outcomes only

No studies found 56 · 19.3%GRADE not reported 21 · 7.2%Very low 61 · 21%Low 62 · 21.4%Moderate 39 · 13.4%High 51 · 17.6%

Intervention not reported

Infants with Grade 3/4 Laboratory Abnormalities · breastfeeding infants of HIV‐infected mothers

It is very uncertain whether the intervention changes infants with Grade 3/4 Laboratory Abnormalities (very low certainty).

1 finding from 1 review

Intervention not reported

The number of patients experiencing abnormal dreams · Patients with memory disorder in multiple sclerosis

The intervention probably leads to higher the number of patients experiencing abnormal dreams (moderate certainty).

1 finding from 1 review

Comparison of plasma transfusions vs no plasma transfusions when the INR is 1.5 prior to central venous catheter insertion

Respiratory deterioration attributable to transfusion‐associated circulatory overload (TACO), transfusion‐related acute lung injury (TRALI) or transfusion‐associated dyspnoea (TAD) · people with abnormal coagulation requiring a central venous catheter

The review found no eligible studies for this question.

1 finding from 1 review

Comparison of plasma transfusions vs no plasma transfusions when the INR is 1.5 prior to central venous catheter insertion

Number of participants with minor procedure‐related bleeding within 7 days of surgery · people with abnormal coagulation requiring a central venous catheter

It is very uncertain whether comparison of plasma transfusions changes minor procedure‐related bleeding compared with no plasma transfusions when the INR is 1.5 prior to central venous… (very low certainty).

1 finding from 1 review

Comparison of plasma transfusions vs no plasma transfusions when the INR is 1.5 prior to central venous catheter insertion

Proportion of participants receiving plasma transfusions · people with abnormal coagulation requiring a central venous catheter

The review found no eligible studies for this question.

1 finding from 1 review