Cochrane · systematic review · CD011756
Plasma transfusions prior to insertion of central lines for people with abnormal coagulation
Hall, DP, Estcourt, LJ, Doree, C, et al. · Cochrane Database of Systematic Reviews · 2016 · Cochrane Library
HaematologyAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
7
current version
GRADE rated
2
No studies
5
Included studies
NR
No studies 5 · 71.4%Ungraded 0 · 0%Very low 2 · 28.6%Low 0 · 0%Moderate 0 · 0%High 0 · 0%
Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.
Questions and results
Comparison of plasma transfusions versus no plasma transfusions when the INR is 1.5 prior to central venous catheter insertion
Population: people with abnormal coagulation requiring a central venous catheter
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Major procedure‐related bleeding Comparison of plasma transfusions vs no plasma transfusions when the INR is 1.5 prior to central venous catheter insertion | no estimate extracted | 1 study · 58 participants | Very low Downgraded: risk of bias, imprecision |
All‐cause mortality Comparison of plasma transfusions vs no plasma transfusions when the INR is 1.5 prior to central venous catheter insertion | no estimate extracted | NR | No studies |
Respiratory deterioration attributable to transfusion‐associated circulatory overload (TACO), transfusion‐related acute lung injury (TRALI) or transfusion‐associated dyspnoea (TAD) Comparison of plasma transfusions vs no plasma transfusions when the INR is 1.5 prior to central venous catheter insertion | no estimate extracted | NR | No studies |
Minor procedure‐related bleeding Comparison of plasma transfusions vs no plasma transfusions when the INR is 1.5 prior to central venous catheter insertion | RR 0.67 [0.12, 3.7] | 1 study · 58 participants | Very low Downgraded: risk of bias, imprecision |
Proportion of participants receiving plasma transfusions Comparison of plasma transfusions vs no plasma transfusions when the INR is 1.5 prior to central venous catheter insertion | no estimate extracted | NR | No studies |
Line‐related complications Comparison of plasma transfusions vs no plasma transfusions when the INR is 1.5 prior to central venous catheter insertion | no estimate extracted | NR | No studies |
Quality of life Comparison of plasma transfusions vs no plasma transfusions when the INR is 1.5 prior to central venous catheter insertion | no estimate extracted | NR | No studies |