Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

2,640 questions · 2,709 findings · 446 reviews

No studies found 593 · 21.9%GRADE not reported 241 · 8.9%Very low 538 · 19.9%Low 706 · 26.1%Moderate 516 · 19%High 115 · 4.2%

Mortality: prone position vs supine

Subgroup analysis of longer‐term mortality: severe hypoxaemiaAlive or dead · adults with acute respiratory failure

Mortality: prone position probably leads to lower subgroup analysis of longer‐term mortality: severe hypoxaemiaAlive… compared with supine (moderate certainty).

1 finding from 1 review

Mortality: prone position vs supine

Subgroup analysis of longer‐term mortality: lower tidal volume ventilationAlive or dead · adults with acute respiratory failure

Mortality: prone position probably leads to lower subgroup analysis of longer‐term mortality: lower tidal volume… compared with supine (moderate certainty).

1 finding from 1 review

Mortality: prone position vs supine

Subgroup analysis of longer‐term mortality: ARDS onlyAlive or dead · adults with acute respiratory failure

Mortality: prone position showed no clear difference in subgroup analysis of longer‐term mortality: ARDS onlyAlive or dead compared with supine (moderate certainty).

1 finding from 1 review

Mortality: prone position vs supine

Subgroup analysis of longer‐term mortality: ≥ 16 hours/d proneAlive or dead · adults with acute respiratory failure

Mortality: prone position probably leads to lower subgroup analysis of longer‐term mortality: ≥ 16 hours/d proneAlive… compared with supine (moderate certainty).

1 finding from 1 review

Mortality: prone position vs supine

Subgroup analysis of longer‐term mortality: enrolment ≤ 48 hours after entry criteria/ventilationAlive or dead · adults with acute respiratory failure

Mortality: prone position probably leads to lower subgroup analysis of longer‐term mortality: enrolment ≤ 48 hours… compared with supine (moderate certainty).

1 finding from 1 review

Ketoconazole vs ciclopirox

Failure to achieve complete resolution (long term) ‐ Face only Clinical assessment · patients with seborrhoeic dermatitis

Ketoconazole showed no clear difference in failure to achieve complete resolution (long term) ‐ Face only… compared with ciclopirox (low certainty).

1 finding from 1 review

Intervention not reported

Mortality within the longest · surgical patients with need for abdominal, caesarean section, orthopaedic or breast surgery

The intervention showed no clear difference in mortality within the longest (low certainty).

1 finding from 1 review

Intervention not reported

Mortality within the longest · surgical patients with need for abdominal, caesarean section, orthopaedic or breast surgery

It is very uncertain whether the intervention changes mortality within the longest (very low certainty).

1 finding from 1 review

Intervention not reported

Live birth or ongoing pregnancy Short protocol vs long protocol · subfertile women

The intervention showed no clear difference in live birth or ongoing pregnancy Short protocol vs long protocol (low certainty).

1 finding from 1 review

Intervention not reported

Live birth/ongoing pregnancy ‐ short vs long protocol · subfertile women

The intervention showed no clear difference in live birth/ongoing pregnancy ‐ short vs long protocol (low certainty).

1 finding from 1 review

Intervention not reported

OHSS ‐ short vs long protocol · subfertile women

The review found no eligible studies for this question.

1 finding from 1 review

Antihistamines vs placebo

Change in severity of overall symptoms: long‐term (6 to 10 days) Subjective severity score · patients with common cold

Antihistamines showed no clear difference in change in severity of overall symptoms: long‐term (6 to 10 days)… compared with placebo (high certainty).

1 finding from 1 review

Sedating antihistamines vs placebo

Change in severity of overall symptoms: long‐term (6 to 10 days) Subjective severity score · patients with common cold

Sedating antihistamines showed no clear difference in change in severity of overall symptoms: long‐term (6 to 10 days)… compared with placebo (high certainty).

1 finding from 1 review