Cochrane · systematic review · CD007884
Endoscopic or surgical intervention for painful obstructive chronic pancreatitis
Ahmed Ali, U, Pahlplatz, JM, Nealon, WH, et al. · Cochrane Database of Systematic Reviews · 2015 · Cochrane Library
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
13
current version
GRADE rated
10
No studies
3
Included studies
NR
No studies 3 · 23.1%Ungraded 0 · 0%Very low 0 · 0%Low 5 · 38.5%Moderate 5 · 38.5%High 0 · 0%
Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.
Questions and results
Show all 2 versionsEndoscopy compared with surgery for painful obstructive chronic pancreatitis
Population: participants with painful obstructive chronic pancreatitis
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Pain relief ‐ middle‐term Endoscopy vs surgery | RR 1.62 [1.22, 2.15] | 2 studies · 111 participants | Moderate Downgraded: risk of bias, imprecision |
Pain relief ‐ long‐term Endoscopy vs surgery | RR 1.56 [1.18, 2.05] | 2 studies · 103 participants | Moderate Downgraded: risk of bias, imprecision |
Major complications and mortality Endoscopy vs surgery | no estimate extracted | 2 studies · 179 participants | Low Downgraded: risk of bias, imprecision |
Quality of life ‐ long‐term SF‐36 ‐ Physical health at 2 years. Scale from 0 to 100 Endoscopy vs surgery | no estimate extracted | 1 study · 31 participants | Moderate Downgraded: risk of bias, imprecision |
Quality of life ‐ long‐term SF‐36 ‐ Mental health at 2 years. Scale from 0 to 100 Endoscopy vs surgery | no estimate extracted | 1 study · 31 participants | Moderate Downgraded: risk of bias, imprecision |
Endocrine pancreatic insufficiency (new onset) ‐ long‐term Endoscopy vs surgery | RR 0.92 [0.54, 1.55] | 2 studies · 95 participants | Low Downgraded: risk of bias, imprecision |
Exocrine pancreatic insufficiency (new onset) ‐ long‐term Endoscopy vs surgery | RR 0.5 [0.19, 1.33] | 1 study · 10 participants | Moderate Downgraded: risk of bias, imprecision |
Surgery compared with conservative treatment for painful obstructive chronic pancreatitis
Population: participants with painful obstructive chronic pancreatitis
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Pain relief Surgery vs conservative treatment | RR 7.1 [1.93, 25.8] | 1 study · 32 participants | Low Downgraded: risk of bias |
Major complications ‐ not reported Surgery vs conservative treatment | no estimate extracted | NR | No studies |
Mortality ‐ not reported Surgery vs conservative treatment | no estimate extracted | NR | No studies |
Quality of life ‐ not measured Surgery vs conservative treatment | no estimate extracted | NR | No studies |
Endocrine pancreatic insufficiency (new onset) Surgery vs conservative treatment | RR 0.23 [0.06, 0.87] | 1 study · 25 participants | Low Downgraded: risk of bias |
Exocrine pancreatic insufficiency (new onset) Surgery vs conservative treatment | RR 0.08 [0.01, 0.57] | 1 study · 29 participants | Low Downgraded: risk of bias |