Cochrane · systematic review · CD008884
The effects of high perioperative inspiratory oxygen fraction for adult surgical patients
Wetterslev, J, Meyhoff, CS, Jørgensen, LN, et al. · Cochrane Database of Systematic Reviews · 2015 · Cochrane Library
AnaesthesiaAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
7
current version
GRADE rated
7
No studies
0
Included studies
NR
No studies 0 · 0%Ungraded 0 · 0%Very low 1 · 14.3%Low 4 · 57.1%Moderate 2 · 28.6%High 0 · 0%
Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.
Questions and results
Summary of findings in randomized clinical trials with overall low risk of bias and in all trials
Population: surgical patients with need for abdominal, caesarean section, orthopaedic or breast surgery
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Mortality within the longest | RR 1.12 [0.93, 1.36] | 3 studies · 4758 participants | Low Downgraded: risk of bias, imprecision |
Mortality within the longest | RR 1.07 [0.87, 1.33] | 6 studies · 4525 participants | Very low Downgraded: risk of bias, imprecision |
Mortality within 30 days of | 0.99 [0.61, 1.6] | 3 studies · 4758 participants | Moderate Downgraded: risk of bias, imprecision |
Mortality within 30 days of | 0.83 [0.54, 1.29] | 6 studies · 4525 participants | Low Downgraded: risk of bias, imprecision |
Surgical site infection within 30 days in trials with low risk of bias (14 days to 30 days) | RR 0.86 [0.63, 1.17] | 5 studies · 4201 participants | Low Downgraded: risk of bias, imprecision |
Surgical site infection within 30 days, irrespective of risk of bias (14 days to 30 days) | RR 0.87 [0.71, 1.07] | 15 studies · 7229 participants | Low Downgraded: risk of bias, imprecision |
Respiratory insufficiency | RR 1.25 [0.79, 1.99] | 1 study · 1386 participants | Moderate Downgraded: risk of bias, imprecision |