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What do systematic reviews say?

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Evidence found and GRADE certainty

2,209 questions · 2,322 findings · 227 reviews · Headline outcomes only

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No studies found 644 · 27.7%GRADE not reported 135 · 5.8%Very low 591 · 25.5%Low 582 · 25.1%Moderate 309 · 13.3%High 61 · 2.6%

CBT vs active control

Participant‐reported pain relief of 30% or greater · chronic pain (excluding headache) in adults
2 findings from 1 review

CBT vs active control

Pain intensity (number of people with ≥ 50% improvement) · chronic pain (excluding headache) in adults
2 findings from 1 review

CBT vs active control

Functional disability at 3 months ‐ not measured · chronic pain (excluding headache) in adults
2 findings from 1 review

CBT vs active control

Quality of life (Higher scores indicate improvement) · chronic pain (excluding headache) in adults
2 findings from 1 review

Silicone hydrogel vs hydrogel soft contact lenses

Comfort · Adults with refractive errors

The review found no eligible studies for this question.

3 findings from 1 review

Silicone hydrogel vs hydrogel soft contact lenses

Proportion of participants who discontinued contact lens wear, at 1 week (RR < 1 favored) · Adults with refractive errors

It is very uncertain whether silicone hydrogel changes proportion of participants who discontinued contact lens wear, at 1… compared with hydrogel soft contact lenses (very low certainty).

1 finding from 1 review

Silicone hydrogel vs hydrogel soft contact lenses

Corneal staining scores, at 1 week (MD < 0 favored) · Adults with refractive errors

It is very uncertain whether silicone hydrogel changes corneal staining scores, at 1 week (MD < 0 favored) compared with hydrogel soft contact lenses (very low certainty).

1 finding from 1 review

Silicone hydrogel vs hydrogel soft contact lenses

Conjunctival staining scores, at 1 month (MD < 0 favored) · Adults with refractive errors

It is very uncertain whether silicone hydrogel changes conjunctival staining scores, at 1 month (MD < 0 favored) compared with hydrogel soft contact lenses (very low certainty).

1 finding from 1 review

Summary of findings table ‐ Psychological interventions vs inactive control (usual care care, attention control, waitlist)

Substance use ‐ post‐intervention ‐ not reported · for parents who are experiencing CPTSD symptoms or have experienced maltreatment in their childhood

Summary of findings table ‐ Psychological interventions showed no clear difference in substance use ‐ post‐interventiong compared with inactive control (usual care care, attention control, waitlist) (low certainty).

1 finding from 1 review

Summary of findings table ‐ Psychological interventions vs inactive control (usual care care, attention control, waitlist)

Parent relationship quality ‐ not reported · for parents who are experiencing CPTSD symptoms or have experienced maltreatment in their childhood
1 finding from 1 review

Summary of findings table ‐ Psychological interventions vs inactive control (usual care care, attention control, waitlist)

Parental self‐harm ‐ post‐intervention ‐ not reported · for parents who are experiencing CPTSD symptoms or have experienced maltreatment in their childhood

The review found no eligible studies for this question.

1 finding from 1 review