Cochrane · systematic review · CD014791
Silicone hydrogel versus hydrogel soft contact lenses for differences in patient‐reported eye comfort and safety
Haworth, K, Travis, D, Leslie, L, et al. · Cochrane Database of Systematic Reviews · 2023 · Cochrane Library
Eyes and VisionAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
7
current version
GRADE rated
6
No studies
1
Included studies
NR
No studies 1 · 14.3%Ungraded 0 · 0%Very low 6 · 85.7%Low 0 · 0%Moderate 0 · 0%High 0 · 0%
Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.
Questions and results
Silicone hydrogel versus hydrogel soft contact lenses for differences in patient‐reported comfort and safety
Population: adults with refractive errors
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Mean change in patient‐reported comfort score from baseline using CLDEQ‐8 Silicone hydrogel vs hydrogel soft contact lenses | no estimate extracted | NR | No studies |
Mean change in patient‐reported comfort score from baseline using OSDI, at 1 month (MD < 0 favored) Silicone hydrogel vs hydrogel soft contact lenses | no estimate extracted | 1 study · 47 participants | Very low Downgraded: risk of bias, imprecision |
Mean change in patient‐reported comfort score from baseline using VAS, at 1 week (MD > 0 favored) Silicone hydrogel vs hydrogel soft contact lenses | MD 0.55 [0.16, 0.94] | 1 study · 240 participants | Very low Downgraded: risk of bias, imprecision |
Proportion of participants who discontinued contact lens wear, at 1 week (RR < 1 favored) Silicone hydrogel vs hydrogel soft contact lenses | RR 0.64 [0.11, 3.74] | 1 study · 248 participants | Very low Downgraded: risk of bias, imprecision |
Corneal staining scores, at 1 week (MD < 0 favored) Silicone hydrogel vs hydrogel soft contact lenses | no estimate extracted | 1 study · 243 participants | Very low Downgraded: risk of bias, imprecision |
Conjunctival staining scores, at 1 month (MD < 0 favored) Silicone hydrogel vs hydrogel soft contact lenses | MD 0.2 | 1 study · 80 participants | Very low Downgraded: risk of bias, imprecision |
Proportion of participants with vision‐threatening adverse events (RR < 1 favored) Silicone hydrogel vs hydrogel soft contact lenses | no estimate extracted | 4 participants | Very low Downgraded: risk of bias, imprecision |