Streptococcus viridans count (CFU/mL) · Children and/or adolescents (<18 years) without background systemic disease
Only one trial (Mishra 2014) reported S. viridans count, showing a higher count with probiotics (MD 0.40 CFU/mL, 95%CI 0.33 to 0.47); not pooled or GRADE-rated.
1 finding from 1 review
Enamel demineralization (QLF ΔF) · Human tooth enamel specimens, sound/intact (in vitro)
Er:YAG laser irradiation significantly reduced enamel mineral loss versus untreated control (SMD -2.09, 95% CI -3.29 to -0.88; 4 in vitro studies; ungraded).
1 finding from 1 review
SMD -2.09 [-3.29, -0.88]
4 studies
GRADE not reported
Streptococcus mutans count · Children and adolescents aged 0-18 years with non-syndromic cleft lip and palate (CLP)
No difference in mean Streptococcus mutans presence was reported; GRADE was not reported.
1 finding from 1 review
Intervention not reported
Overall success (composite of clinical and radiographic success)
1 finding from 1 review
Caries in primary teeth: dmft (3 years) · Institutionalized orphan children (roughly 3 to 18 years)
Primary-teeth caries experience (dmf) was higher in institutionalized children than parented children but not significantly so (pooled MD 0.64; very low certainty).
1 finding from 1 review
Dental caries prevalence · Brazilian children in primary dentition (BMI classified by CDC 2000 growth charts)
Overweight may make little or no difference to the odds of dental caries in the primary dentition (very low certainty).
1 finding from 1 review
Rotation of the mandibular first premolar · Children and adolescents after extraction of a mandibular permanent first molar (before eruption of the second molar)
After mandibular first molar extraction, the first premolar was rotated in about 38% of cases (2 studies; very imprecise; not GRADE-rated).
1 finding from 1 review
Mean DFR (decayed, filled root teeth) · adults
Patients with periodontitis had a significantly higher mean DFR (WMD 1.13).
1 finding from 1 review
Spontaneous space closure · Children and adolescents with maxillary permanent first molar extraction
In the maxilla, M2 Demirjian stages A-D were not associated with a statistically significant difference in space closure odds.
1 finding from 1 review
Incidence of new ICLs (proportion of subjects developing new lesions) · Patients undergoing fixed orthodontic treatment with fixed (multibracket) appliances, followed for development of new ICLs
About 48% of patients developed new ICLs during fixed orthodontic treatment (pooled incidence 0.48, 95% CI 0.33-0.63; very low certainty; very high heterogeneity).
1 finding from 1 review
Intervention not reported
Comparable diagnostic accuracy (photographic vs visual examination)
1 finding from 1 review
Prevalence of ICLs (proportion of tooth surfaces affected) · Patients (permanent dentition) during or after fixed orthodontic treatment with fixed (multibracket) appliances
About 22% of tooth surfaces showed ICLs during/after fixed orthodontic treatment (pooled 0.22, 95% CI 0.14-0.33; very low certainty; extreme heterogeneity).
1 finding from 1 review
Prevalence of ICLs (proportion of subjects affected) · Patients (permanent dentition) during or after fixed orthodontic treatment with fixed (multibracket) appliances
Around 57% of patients had ICLs during or after fixed orthodontic treatment (pooled prevalence 0.57, 95% CI 0.48-0.65; very low certainty; very high heterogeneity).
1 finding from 1 review
Periodontal conditions (gingival inflammation, bleeding on probing, probing depth, clinical attachment loss) · Children and adolescents aged 0-18 years with non-syndromic cleft lip and palate (CLP)
Narrative synthesis of 6 studies suggests children/adolescents with CLP have poorer periodontal status (higher gingival and plaque indices, deeper probing, more bleeding and attachment loss) and harbor periodontopathogens; no pooled estimate and the evidence is ungraded.
1 finding from 1 review
Crown caries · adults
Periodontitis was associated with a small increase in crown caries odds (OR 1.03).
1 finding from 1 review
d/D dft/DFT or dmft/DMFT score differences · Children and adults with primary or permanent dentition
Eight studies calculated caries-score differences; six reported no significant difference, one underestimation, and one overestimation with teledentistry.
1 finding from 1 review
no estimate extracted
8 studies
GRADE not reported
Periodontitis (clinical attachment loss) · Adults in case-control studies (oral cancer patients vs healthy controls)
Clinical attachment loss was significantly greater in oral cancer patients than controls (SMD 1.94, 95% CI 0.22-3.66), though heterogeneity was very high (I2=96.7%); ungraded.
1 finding from 1 review
Intervention not reported
Dental caries (early childhood caries)
1 finding from 1 review
AOR 6.7
1 study
GRADE not reported
Dental caries prevalence · Nigerian individuals, including children and adults, with primary or permanent dentition
High-frequency sugar consumption was associated with 18% higher but non-significant odds of dental caries in Nigeria (OR 1.18, 95% CI 0.87 to 1.59; I2=36%; ungraded).
1 finding from 1 review
White spot lesion incidence · High caries-risk patients: fixed-orthodontic-appliance patients and children with partially erupted permanent molars
Low-power CO2 laser (LLLT) is associated with a lower incidence of new white spot lesions than placebo (OR 0.21, CI 0.15 to 0.30; ungraded, 3 RCTs, considerable heterogeneity I2=71%).
1 finding from 1 review