Gap finder

Search review questions

Each row is one question a systematic review asked: who, what, compared with what, and which outcome, with the effect it found and how certain that is. Every word you type has to appear somewhere in the question, and the closest matches are ranked first.

Limit to evidence status or GRADE (optional)

75,239 questions in 5,342 reviews

current versions
No studies 15,213 · 20.2%Ungraded 10,323 · 13.7%Very low 17,528 · 23.3%Low 17,951 · 23.9%Moderate 11,190 · 14.9%High 3,034 · 4%

Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.

QuestionEffectEvidenceStatus / GRADE
White noise vs standard care
Physiological indicators · neonates with mechanical ventilation
Non‐pharmacological interventions for the prevention of pain during endotracheal suctioning in ventilated… (2024) · Cochrane
no estimate extractedNRNo studies
Facilitated tucking / four‐handed care / gentle human touch vs standard care
PIPP during endotracheal suctioning Range of scale 0 to 21. Lower score = less pain · neonates with mechanical ventilation
Non‐pharmacological interventions for the prevention of pain during endotracheal suctioning in ventilated… (2024) · Cochrane
no estimate extracted4 studies · 148 participantsModerate
White noise vs standard care
Heart rate · neonates with mechanical ventilation
Non‐pharmacological interventions for the prevention of pain during endotracheal suctioning in ventilated… (2024) · Cochrane
no estimate extracted1 study · 40 participantsLow
White noise vs standard care
SaO 2 · neonates with mechanical ventilation
Non‐pharmacological interventions for the prevention of pain during endotracheal suctioning in ventilated… (2024) · Cochrane
MD 2.251 study · 40 participantsLow
White noise vs standard care
Behavioural indicators · neonates with mechanical ventilation
Non‐pharmacological interventions for the prevention of pain during endotracheal suctioning in ventilated… (2024) · Cochrane
no estimate extractedNRNo studies
White noise vs standard care
— · neonates with mechanical ventilation
Non‐pharmacological interventions for the prevention of pain during endotracheal suctioning in ventilated… (2024) · Cochrane
no estimate extractedNRNo studies
Facilitated tucking / four‐handed care / gentle human touch vs standard care
Physiological indicators · neonates with mechanical ventilation
Non‐pharmacological interventions for the prevention of pain during endotracheal suctioning in ventilated… (2024) · Cochrane
no estimate extractedNRNo studies
Facilitated tucking / four‐handed care / gentle human touch vs standard care
Heart rate · neonates with mechanical ventilation
Non‐pharmacological interventions for the prevention of pain during endotracheal suctioning in ventilated… (2024) · Cochrane
no estimate extracted2 studies · 80 participantsLow
Facilitated tucking / four‐handed care / gentle human touch vs standard care
SaO 2 during endotracheal suctioning · neonates with mechanical ventilation
Non‐pharmacological interventions for the prevention of pain during endotracheal suctioning in ventilated… (2024) · Cochrane
MD 0.872 studies · 80 participantsLow
Facilitated tucking / four‐handed care / gentle human touch vs standard care
Behavioural indicators · neonates with mechanical ventilation
Non‐pharmacological interventions for the prevention of pain during endotracheal suctioning in ventilated… (2024) · Cochrane
no estimate extractedNRNo studies
Facilitated tucking / four‐handed care / gentle human touch vs standard care
SDB during endotracheal suctioning · neonates with mechanical ventilation
Non‐pharmacological interventions for the prevention of pain during endotracheal suctioning in ventilated… (2024) · Cochrane
no estimate extracted1 study · 20 participantsLow
Facilitated tucking / four‐handed care / gentle human touch vs standard care
SRB during endotracheal suctioning · neonates with mechanical ventilation
Non‐pharmacological interventions for the prevention of pain during endotracheal suctioning in ventilated… (2024) · Cochrane
MD 0.9 [0.2, 1.6]1 study · 20 participantsLow
Facilitated tucking / four‐handed care / gentle human touch vs standard care
— · neonates with mechanical ventilation
Non‐pharmacological interventions for the prevention of pain during endotracheal suctioning in ventilated… (2024) · Cochrane
no estimate extractedNRNo studies
Mindfulness‐based interventions (MBIs) vs active comparators
Clinical CVD events · people at high risk of or withcardiovascular disease
Meditation for the primary and secondary prevention of cardiovascular disease (2024) · Cochrane
no estimate extractedNRNo studies
Mindfulness‐based interventions (MBIs) vs non‐active comparators
Clinical CVD events (CVD mortality and non‐fatal MI) · people at high risk of or withcardiovascular disease
Meditation for the primary and secondary prevention of cardiovascular disease (2024) · Cochrane
RR 0.94 [0.37, 2.42]1 study · 110 participantsVery low
Mindfulness‐based interventions (MBIs) vs non‐active comparators
Systolic blood pressure (mmHg), change from baseline · people at high risk of or withcardiovascular disease
Meditation for the primary and secondary prevention of cardiovascular disease (2024) · Cochrane
no estimate extracted9 studies · 379 participantsLow
Mindfulness‐based interventions (MBIs) vs non‐active comparators
Diastolic blood pressure (mmHg), change from baseline · people at high risk of or withcardiovascular disease
Meditation for the primary and secondary prevention of cardiovascular disease (2024) · Cochrane
no estimate extracted9 studies · 379 participantsLow
Mindfulness‐based interventions (MBIs) vs non‐active comparators
Anxiety, change from baseline · people at high risk of or withcardiovascular disease
Meditation for the primary and secondary prevention of cardiovascular disease (2024) · Cochrane
no estimate extracted9 studies · 533 participantsLow
Mindfulness‐based interventions (MBIs) vs non‐active comparators
Depression, change from baseline · people at high risk of or withcardiovascular disease
Meditation for the primary and secondary prevention of cardiovascular disease (2024) · Cochrane
no estimate extracted15 studies · 912 participantsLow
Mindfulness‐based interventions (MBIs) vs non‐active comparators
Perceived stress, change from baseline · people at high risk of or withcardiovascular disease
Meditation for the primary and secondary prevention of cardiovascular disease (2024) · Cochrane
no estimate extracted11 studies · 708 participantsLow
Mindfulness‐based interventions (MBIs) vs non‐active comparators
Well‐being · people at high risk of or withcardiovascular disease
Meditation for the primary and secondary prevention of cardiovascular disease (2024) · Cochrane
no estimate extracted2 studies · 198 participantsModerate
Mindfulness‐based interventions (MBIs) vs non‐active comparators
Adverse events · people at high risk of or withcardiovascular disease
Meditation for the primary and secondary prevention of cardiovascular disease (2024) · Cochrane
RR 5 [0.27, 91.52]1 study · 18 participantsLow
Mindfulness‐based interventions (MBIs) vs non‐active comparators
Smoking cessation · people at high risk of or withcardiovascular disease
Meditation for the primary and secondary prevention of cardiovascular disease (2024) · Cochrane
RR 1.36 [0.86, 2.13]2 studies · 453 participantsLow
Transcendental meditation (TM) vs active comparators
Clinical CVD events (CVD mortality, non‐fatal MI and stroke, revascularisations) · people at high risk of or with cardiovascular disease
Meditation for the primary and secondary prevention of cardiovascular disease (2024) · Cochrane
RR 0.91 [0.56, 1.49]1 study · 201 participantsLow
Mindfulness‐based interventions (MBIs) vs active comparators
Systolic blood pressure (mmHg), change from baseline · people at high risk of or withcardiovascular disease
Meditation for the primary and secondary prevention of cardiovascular disease (2024) · Cochrane
no estimate extracted6 studies · 388 participantsLow
Transcendental meditation (TM) vs active comparators
Systolic blood pressure (mmHg), change from baseline · people at high risk of or with cardiovascular disease
Meditation for the primary and secondary prevention of cardiovascular disease (2024) · Cochrane
no estimate extracted8 studies · 774 participantsModerate
Transcendental meditation (TM) vs active comparators
Diastolic blood pressure (mmHg), change from baseline · people at high risk of or with cardiovascular disease
Meditation for the primary and secondary prevention of cardiovascular disease (2024) · Cochrane
no estimate extracted8 studies · 774 participantsLow
Transcendental meditation (TM) vs active comparators
Anxiety, change from baseline · people at high risk of or with cardiovascular disease
Meditation for the primary and secondary prevention of cardiovascular disease (2024) · Cochrane
no estimate extracted3 studies · 200 participantsLow
Transcendental meditation (TM) vs active comparators
Depression, change from baseline · people at high risk of or with cardiovascular disease
Meditation for the primary and secondary prevention of cardiovascular disease (2024) · Cochrane
no estimate extracted5 studies · 421 participantsModerate
Transcendental meditation (TM) vs active comparators
Perceived stress, change from baseline · people at high risk of or with cardiovascular disease
Meditation for the primary and secondary prevention of cardiovascular disease (2024) · Cochrane
no estimate extracted3 studies · 194 participantsVery low
Transcendental meditation (TM) vs active comparators
Well‐being · people at high risk of or with cardiovascular disease
Meditation for the primary and secondary prevention of cardiovascular disease (2024) · Cochrane
no estimate extractedNRNo studies
Transcendental meditation (TM) vs active comparators
Adverse events · people at high risk of or with cardiovascular disease
Meditation for the primary and secondary prevention of cardiovascular disease (2024) · Cochrane
no estimate extractedNRNo studies
Transcendental meditation (TM) vs active comparators
Smoking cessation · people at high risk of or with cardiovascular disease
Meditation for the primary and secondary prevention of cardiovascular disease (2024) · Cochrane
no estimate extractedNRNo studies
Transcendental meditation (TM) vs non‐active comparators
Clinical CVD events · people at high risk of or withcardiovascular disease
Meditation for the primary and secondary prevention of cardiovascular disease (2024) · Cochrane
no estimate extractedNRNo studies
Transcendental meditation (TM) vs non‐active comparators
Systolic blood pressure (mmHg), change from baseline · people at high risk of or withcardiovascular disease
Meditation for the primary and secondary prevention of cardiovascular disease (2024) · Cochrane
no estimate extracted2 studies · 139 participantsLow
Mindfulness‐based interventions (MBIs) vs active comparators
Diastolic blood pressure (mmHg), change from baseline · people at high risk of or withcardiovascular disease
Meditation for the primary and secondary prevention of cardiovascular disease (2024) · Cochrane
no estimate extracted6 studies · 388 participantsLow
Transcendental meditation (TM) vs non‐active comparators
Diastolic blood pressure (mmHg), change from baseline · people at high risk of or withcardiovascular disease
Meditation for the primary and secondary prevention of cardiovascular disease (2024) · Cochrane
no estimate extracted2 studies · 139 participantsLow
Transcendental meditation (TM) vs non‐active comparators
Anxiety, change from baseline · people at high risk of or withcardiovascular disease
Meditation for the primary and secondary prevention of cardiovascular disease (2024) · Cochrane
no estimate extracted1 study · 112 participantsLow
Transcendental meditation (TM) vs non‐active comparators
Depression, change from baseline · people at high risk of or withcardiovascular disease
Meditation for the primary and secondary prevention of cardiovascular disease (2024) · Cochrane
no estimate extracted1 study · 112 participantsLow
Transcendental meditation (TM) vs non‐active comparators
Perceived stress · people at high risk of or withcardiovascular disease
Meditation for the primary and secondary prevention of cardiovascular disease (2024) · Cochrane
no estimate extractedNRNo studies
Transcendental meditation (TM) vs non‐active comparators
Well‐being · people at high risk of or withcardiovascular disease
Meditation for the primary and secondary prevention of cardiovascular disease (2024) · Cochrane
no estimate extractedNRNo studies
Transcendental meditation (TM) vs non‐active comparators
Adverse events · people at high risk of or withcardiovascular disease
Meditation for the primary and secondary prevention of cardiovascular disease (2024) · Cochrane
no estimate extractedNRNo studies
Transcendental meditation (TM) vs non‐active comparators
Smoking cessation · people at high risk of or withcardiovascular disease
Meditation for the primary and secondary prevention of cardiovascular disease (2024) · Cochrane
no estimate extractedNRNo studies
Mindfulness‐based interventions (MBIs) vs active comparators
Anxiety, change from baseline · people at high risk of or withcardiovascular disease
Meditation for the primary and secondary prevention of cardiovascular disease (2024) · Cochrane
no estimate extracted9 studies · 438 participantsModerate
Mindfulness‐based interventions (MBIs) vs active comparators
Depression, change from baseline · people at high risk of or withcardiovascular disease
Meditation for the primary and secondary prevention of cardiovascular disease (2024) · Cochrane
no estimate extracted11 studies · 595 participantsModerate
Mindfulness‐based interventions (MBIs) vs active comparators
Perceived stress, change from baseline · people at high risk of or withcardiovascular disease
Meditation for the primary and secondary prevention of cardiovascular disease (2024) · Cochrane
no estimate extracted6 studies · 357 participantsModerate
Mindfulness‐based interventions (MBIs) vs active comparators
Well‐being · people at high risk of or withcardiovascular disease
Meditation for the primary and secondary prevention of cardiovascular disease (2024) · Cochrane
no estimate extracted1 study · 63 participantsLow
Mindfulness‐based interventions (MBIs) vs active comparators
Adverse events · people at high risk of or withcardiovascular disease
Meditation for the primary and secondary prevention of cardiovascular disease (2024) · Cochrane
no estimate extractedNRNo studies
Mindfulness‐based interventions (MBIs) vs active comparators
Smoking cessation · people at high risk of or withcardiovascular disease
Meditation for the primary and secondary prevention of cardiovascular disease (2024) · Cochrane
RR 1.45 [0.78, 2.68]6 studies · 1087 participantsLow
TG4010 added to chemotherapy vs chemotherapy alone
Overall survival · adults with advanced non‐small cell lung cancer (NSCLC)
Therapeutic vaccines for advanced non‐small cell lung cancer (2024) · Cochrane
HR 0.83 [0.65, 1.05]2 studies · 370 participantsLow