Clinical failure · febrile neutropenia
It is very uncertain whether early discontinuation of antibiotic treatment changes clinical failure compared with treatment until neutropenia resolution (very low certainty).
1 finding from 1 review
Bacteraemia · febrile neutropenia
It is very uncertain whether early discontinuation of antibiotic treatment changes any bacteraemia compared with treatment until neutropenia resolution (very low certainty).
1 finding from 1 review
Failure to induce clinical remission at end of study · Patients with active Crohn's disease
Antibiotic leads to lower failure to enter clinical remission compared with placebo (high certainty).
1 finding from 1 review
Failure to achieve clinical response or remission · Patients with active Crohn's disease
Antibiotic with anti‐TNF showed no clear difference in failure to achieve clinical response or remission compared with placebo with anti‐TNF (low certainty).
1 finding from 1 review
Failure to maintain endoscopic remission · Patients with active Crohn's disease
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Adverse events · Patients with active Crohn's disease
Antibiotic with anti‐TNF showed no clear difference in adverse events compared with placebo with anti‐TNF (moderate certainty).
1 finding from 1 review
Serious adverse events · Patients with active Crohn's disease
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Withdrawals due to adverse events · Patients with active Crohn's disease
Antibiotic with anti‐TNF showed no clear difference in withdrawal due to adverse events compared with placebo with anti‐TNF (low certainty).
1 finding from 1 review
Failure to maintain remission · Patients with active Crohn's disease
Antibiotic showed no clear difference in failure to maintain clinical remission compared with placebo (low certainty).
1 finding from 1 review
Failure to achieve clinical response · Patients with active Crohn's disease
Antibiotic probably leads to lower failure to achieve clinical response compared with placebo (moderate certainty).
1 finding from 1 review
Failure to maintain endoscopic remission · Patients with active Crohn's disease
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Adverse events · Patients with active Crohn's disease
Antibiotic showed no clear difference in adverse events compared with placebo (high certainty).
1 finding from 1 review
Serious adverse events · Patients with active Crohn's disease
Antibiotic showed no clear difference in serious adverse events compared with placebo (low certainty).
1 finding from 1 review
Withdrawals due to adverse events · Patients with active Crohn's disease
Antibiotic showed no clear difference in withdrawal due to adverse events compared with placebo (low certainty).
1 finding from 1 review
Failure to induce clinical remission at end of study · Patients with active Crohn's disease
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Failure to maintain remission · Patients with active Crohn's disease
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Treatment failure · adults with scrub typhus
It is very uncertain whether doxycycline changes treatment failure compared with tetracycline (very low certainty).
1 finding from 1 review
Serious adverse events · adults and adolescents with scrub typhus
1 finding from 1 review
Treatment failure · adults with scrub typhus
1 finding from 1 review
Resolution of fever within 48 hours · adults with scrub typhus
It is very uncertain whether rifampicin changes resolution of fever within 48 hours compared with doxycycline (very low certainty).
1 finding from 1 review