Question · asked by 1 review
Antibiotics vs placebo: Adverse events
- Population
- Patients with active Crohn's disease
- Intervention
- Antibiotics
- Comparison
- placebo
- Outcome
- Adverse events
Antibiotic showed no clear difference in adverse events compared with placebo (high certainty).
What each review found
Include earlier review versions| Finding | Effect | Studies | GRADE certainty |
|---|---|---|---|
Antibiotic vs placebo Adverse events · Participants with active CD Antibiotic showed no clear difference in adverse events compared with placebo (high certainty). Antibiotics for induction and maintenance of remission in Crohn's disease (2019) · Cochrane Headline outcomes only | RR 0.87 [0.75, 1.02] | 9 studies · 852 participants | High |
Findings are shown side by side, never pooled across reviews.
The reviews
| Review | Searched up to | Included studies | AMSTAR 2 |
|---|---|---|---|
| Antibiotics for induction and maintenance of remission in Crohn's disease 2019 · Cochrane Headline outcomes only | Not reported | Not extracted | Not assessed |
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How reviews are matched to this question
Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.