Question · asked by 1 review

Antibiotics vs placebo: Failure to induce clinical remission at end of study

Antibiotic leads to lower failure to enter clinical remission compared with placebo (high certainty).

What each review found

Include earlier review versions
FindingEffectStudiesGRADE certainty
Antibiotic vs placebo
Failure to enter clinical remission · Participants with active CD
Antibiotic leads to lower failure to enter clinical remission compared with placebo (high certainty).
Antibiotics for induction and maintenance of remission in Crohn's disease (2019) · Cochrane Headline outcomes only
RR 0.86 [0.76, 0.98]7 studies · 773 participantsHigh

Findings are shown side by side, never pooled across reviews.

The reviews

ReviewSearched up toIncluded studiesAMSTAR 2
Antibiotics for induction and maintenance of remission in Crohn's disease
2019 · Cochrane Headline outcomes only
Not reportedlist not extracted yetNot assessed

Studies behind the findings

None of these reviews ties its included studies to this outcome in the data here. Cochrane reviews and reviews with headline outcomes only do not list their studies yet.

How reviews are matched to this question

Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.