Findings

What do systematic reviews say?

Refine by population, intervention, comparison or outcome
More filters
Evidence found and GRADE certainty

1,310 questions · 1,358 findings · 214 reviews

No studies found 230 · 16.9%GRADE not reported 169 · 12.4%Very low 269 · 19.8%Low 277 · 20.4%Moderate 291 · 21.4%High 122 · 9%

Summary of findings table ‐ Cognitive rehabilitation vs no treatment

Return to work · Treating patients with traumatic brain injury

It is very uncertain whether cognitive rehabilitation changes return to work Assessed by attainment of work within 14 weeks… compared with no treatment (very low certainty).

1 finding from 1 review

Cognitive didactic therapy vs functional experiential therapy

ADL outcome · adult veterans or active duty military service personnel with moderate‐to‐severe traumatic brain injury

Cognitive didactic therapy showed no clear difference in independence in ADL Structured interview compared with functional experiential therapy (low certainty).

1 finding from 1 review

Hospital‐based cognitive rehabilitation vs home programme

Return to work · active duty military personnel within 3 months of moderate‐to‐severe traumatic brain injury

Hospital‐based cognitive rehabilitation showed no clear difference in return to work Return to work status compared with home programme (moderate certainty).

1 finding from 1 review

Cognitive didactic therapy vs functional experiential therapy

Return to work · adult veterans or active duty military service personnel with moderate‐to‐severe traumatic brain injury

Cognitive didactic therapy showed no clear difference in return to work Return to work status compared with functional experiential therapy (moderate certainty).

1 finding from 1 review

Antihypertensive drug therapy vs control

Cardiovascular mortality and morbidity Mean duration of 3.7 years · adults aged 18‐59 years with primary hypertension (mild to moderate systolic or diastolic hypertension)

Antihypertensive drug therapy may leads to lower total cardiovascular mortality + morbidity compared with control (low certainty).

1 finding from 1 review

Antihypertensive drug therapy vs control

Coronary heart disease mortality + morbidity · adults aged 18‐59 years with primary hypertension (mild to moderate systolic or diastolic hypertension)

Antihypertensive drug therapy showed no clear difference in coronary heart disease mortality + morbidity compared with control (low certainty).

1 finding from 1 review

Antihypertensive drug therapy vs control

Withdrawals due to adverse events · adults aged 18‐59 years with primary hypertension (mild to moderate systolic or diastolic hypertension)

It is very uncertain whether antihypertensive drug therapy changes withdrawal due to adverse events compared with control (very low certainty).

1 finding from 1 review

On‐demand deprescribing vs continued use

Adverse drug withdrawal events ‐ esophagitis (endoscopic findings) · people with moderate GERD and mild esophagitis, mean age 48 to 57 years

On‐demand deprescribing may leads to higher adverse drug withdrawal events ‐ esophagitis (endoscopic findings) compared with continued use (low certainty).

1 finding from 1 review