Question · asked by 1 review
Antihypertensive drug therapy vs control: Coronary heart disease mortality + morbidity
- Population
- adults aged 18‐59 years with primary hypertension (mild to moderate systolic or diastolic hypertension)
- Intervention
- Antihypertensive drug therapy
- Comparison
- control
- Outcome
- Coronary heart disease mortality + morbidity
Antihypertensive drug therapy showed no clear difference in coronary heart disease mortality + morbidity compared with control (low certainty).
What each review found
Include earlier review versions| Finding | Effect | Studies | GRADE certainty |
|---|---|---|---|
Antihypertensive drug therapy vs control Coronary heart disease mortality + morbidity · adults aged 18‐59 years with primary hypertension (mild to moderate systolic or diastolic hypertension) Antihypertensive drug therapy showed no clear difference in coronary heart disease mortality + morbidity compared with control (low certainty). Pharmacotherapy for hypertension in adults aged 18 to 59 years (2017) · Cochrane Headline outcomes only | RR 0.99 [0.82, 1.19] | 4 studies · 16241 participants | Low |
Findings are shown side by side, never pooled across reviews.
The reviews
| Review | Searched up to | Included studies | AMSTAR 2 |
|---|---|---|---|
| Pharmacotherapy for hypertension in adults aged 18 to 59 years 2017 · Cochrane Headline outcomes only | Not reported | Not extracted | Not assessed |
How reviews are matched to this question
Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.