Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

583 questions · 638 findings · 60 reviews · Infectious Diseases

No studies found 54 · 8.5%GRADE not reported 98 · 15.4%Very low 118 · 18.5%Low 141 · 22.1%Moderate 141 · 22.1%High 86 · 13.5%

Intervention not reported

Adult worm prevalence detected by ultrasound · people with lymphatic filariasis or communities where lymphatic filariasis is endemic

The intervention showed no clear difference in adult worm prevalence detected by ultrasound (low certainty).

1 finding from 1 review

Intervention not reported

Microfilaraemia (mf) prevalence · people with lymphatic filariasis or communities where lymphatic filariasis is endemic

The intervention showed no clear difference in microfilaraemia (mf) prevalence (high certainty).

1 finding from 1 review

Early ART vs delayed ART initiation

HIV virological suppression at 6 months (viral load < 400 copies/mL) · HIV‐positive people with cryptococcal meningitis

It is very uncertain whether early ART changes HIV virological suppression at 6 months (viral load < 400 copies/mL) compared with delayed ART initiation (very low certainty).

1 finding from 1 review

Health promotion activities vs no intervention

Long‐term tuberculosis prevalence · Individuals of all ages

The review found no eligible studies for this question.

2 findings from 1 review

Intervention not reported

Clinical malaria Subgrouped by presence of malaria prevention or management services · children in malaria‐endemic areas

The intervention may leads to lower clinical malaria Subgrouped by presence of malaria prevention or… (low certainty).

1 finding from 1 review

Antibiotics vs placebo or no treatment

Diarrhoea · patients symptomatic for NTS infection

It is very uncertain whether antibiotics changes presence of diarrhoea at 2‐4 days compared with placebo or no treatment (very low certainty).

2 findings from 1 review