Cochrane · systematic review · CD001167

Antimicrobials for treating symptomatic non‐typhoidal Salmonella infection

Onwuezobe, IA, Oshun, PO, Odigwe, CC · Cochrane Database of Systematic Reviews · 2012 · Cochrane Library

Infectious DiseasesAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
6
current version
GRADE rated
6
No studies
0
Included studies
NR
No studies 0 · 0%Ungraded 0 · 0%Very low 5 · 83.3%Low 1 · 16.7%Moderate 0 · 0%High 0 · 0%

Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.

Questions and results

Antibiotics versus placebo or no treatment for treating symptomatic NTS infection

Population: patients symptomatic for NTS infection
6 questions
OutcomeEffectEvidenceStatus / GRADE
Duration of diarrhoea (days)
Antibiotics vs placebo or no treatment
no estimate extracted4 studies · 202 participantsLow
Downgraded: risk of bias, imprecision, indirectness
Duration of fever (days)
Antibiotics vs placebo or no treatment
no estimate extracted2 studies · 107 participantsVery low
Downgraded: risk of bias, imprecision, indirectness
Duration of illness (days)
Antibiotics vs placebo or no treatment
no estimate extracted2 studies · 116 participantsVery low
Downgraded: risk of bias, imprecision, indirectness
Clinical treatment failure (Persistent or worsening symptoms at the end of treatment)
Antibiotics vs placebo or no treatment
RR 0.88 [0.62, 1.25]7 studies · 440 participantsVery low
Downgraded: risk of bias, imprecision, inconsistency
Presence of diarrhoea at 2‐4 days
Antibiotics vs placebo or no treatment
RR 1.75 [0.42, 7.21]1 study · 46 participantsVery low
Downgraded: risk of bias, imprecision, indirectness
Presence of diarrhoea at 5‐7 days
Antibiotics vs placebo or no treatment
RR 0.83 [0.62, 1.12]2 studies · 192 participantsVery low
Downgraded: risk of bias, imprecision, indirectness