Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

105 questions · 107 findings · 28 reviews

No studies found 7 · 6.5%GRADE not reported 12 · 11.2%Very low 39 · 36.4%Low 30 · 28%Moderate 12 · 11.2%High 7 · 6.5%

Mindfulness vs no treatment or waiting list

Mental health and well‐being: stress or stress perceptionMeasured by: investigators measured stress or stress perception using different instruments; lower scores mean lower stress or stress perception Timing of outcome assessment: post‐intervention
1 finding from 1 review

Antifibrinolytic therapy - locally-applied tranexamic acid (TXA) mouthwash/solution (SoF eligibility: TXA or EACA; all included trials used topical TXA) vs Placebo mouthwash

Number of immediate (less than 24 hours) and delayed (24 hours to 10 days) postoperative bleeding episodes requiring intervention · People on continuous VKA treatment undergoing minor oral surgery or dental extractions (eligibility included DOACs and all ages; all four…

Antifibrinolytic therapy - locally-applied tranexamic acid (TXA)… led to lower number of immediate and delayed postoperative bleeding episodes… compared with placebo (placebo solution/mouthwash); GRADE not reported.

1 finding from 1 review

Intervention not reported

MST vs ECT ‐ cognitive function ‐ immediate memory (high = better; short term) · patients with schizophrenia
1 finding from 1 review

Decompressive surgery plus radiotherapy vs radiotherapy

Ambulation · adults with metastatic extradural spinal cord compression (fit for surgery, paraplegic less than 48 hours, and without multiple discrete…

Decompressive surgery plus radiotherapy may leads to higher ambulation Immediately after completing RT compared with radiotherapy (low certainty).

1 finding from 1 review

Very early cerebral revascularization vs delayed treatment

Perioperative death and strokes · people with recently symptomatic carotid artery stenosis

It is very uncertain whether very early cerebral revascularization changes stroke and Death < 30 days compared with delayed treatment (very low certainty).

2 findings from 1 review