Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

105 questions · 107 findings · 28 reviews

No studies found 7 · 6.5%GRADE not reported 12 · 11.2%Very low 39 · 36.4%Low 30 · 28%Moderate 12 · 11.2%High 7 · 6.5%

IMMEDIATE initiation of cART vs DEFERRED initiation of cART

Patient or population: HIV‐positive, treatment‐naive children aged 24 to 59 months (2 to 5 years old)Settings: Thailand and CambodiaIntervention: IMMEDIATE initiation of cARTComparison: DEFERRED initiation of cART · HIV‐positive, treatment‐naive children aged one to 12 years old

The review found no eligible studies for this question.

1 finding from 1 review

Single-visit root canal treatment vs Multiple-visit root canal treatment (two or more visits)

Patient‐reported pain intensity or pain relief (VAS, NRS or categorical scale) · People aged 10 years or above requiring root canal treatment; permanent teeth with completely formed apex and without internal resorption

Single-visit root canal treatment showed no clear difference in postoperative pain in the immediate postobturation period (up to 72… compared with multiple-visit root canal treatment (two or more visits) (low certainty).

1 finding from 1 review

Single-visit root canal treatment vs Multiple-visit root canal treatment (two or more visits)

Postoperative pain intensity in the immediate postobturation period (up to 72 hours), continuous (VAS) · People aged 10 years or above requiring root canal treatment; permanent teeth with completely formed apex and without internal resorption

Single-visit root canal treatment showed no clear difference in postoperative pain intensity in the immediate postobturation period… compared with multiple-visit root canal treatment (two or more visits) (low certainty).

1 finding from 1 review

Intervention not reported

All‐cause mortality at 2 days ‐ immediate treatment · patients with acute myocardial infarction or stroke1

It is very uncertain whether the intervention changes all‐cause mortality at 2 days ‐ immediate treatment (very low certainty).

1 finding from 1 review

Herbal treatment vs placebo

Participant‐reported pain relief of 30% or greater · adults with neuropathic pain

It is very uncertain whether herbal treatment changes participant‐reported pain relief of 30% or greater Immediately… compared with placebo (very low certainty).

1 finding from 1 review