Immediate treatment vs controls: Mortality at the end of the
Immediate treatment showed no clear difference in mortality at the end of the compared with controls (high certainty).
What each review found
Include earlier review versions| Finding | Effect | Studies | GRADE certainty |
|---|---|---|---|
Immediate treatment vs controls Mortality at the end of the · patients with first unprovoked seizure Immediate treatment showed no clear difference in mortality at the end of the compared with controls (high certainty). Immediate antiepileptic drug treatment, versus placebo, deferred, or no treatment for first unprovoked seizure (2021) · Cochrane Headline outcomes only | RR 1.16 [0.69, 1.95] | 2 studies · 1212 participants | High |
Findings are shown side by side, never pooled across reviews.
The reviews
| Review | Searched up to | Included studies | AMSTAR 2 |
|---|---|---|---|
| Immediate antiepileptic drug treatment, versus placebo, deferred, or no treatment for first unprovoked seizure 2021 · Cochrane Headline outcomes only | Not reported | list not extracted yet | Not assessed |
Studies behind the findings
None of these reviews ties its included studies to this outcome in the data here. Cochrane reviews and reviews with headline outcomes only do not list their studies yet.
How reviews are matched to this question
Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.