Cochrane · systematic review · CD006743
Effect of early treatment with anti‐hypertensive drugs on short and long‐term mortality in patients with an acute cardiovascular event
Perez, MI, Musini, VM, Wright, JM · Cochrane Database of Systematic Reviews · 2009 · Cochrane Library
HypertensionAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
8
current version
GRADE rated
8
No studies
0
Included studies
NR
No studies 0 · 0%Ungraded 0 · 0%Very low 2 · 25%Low 1 · 12.5%Moderate 0 · 0%High 5 · 62.5%
Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.
Questions and results
Immediate and short term administration of nitrates in patients with acute cardiovascular events
Population: patients with acute myocardial infarction1
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
All‐cause mortality at 2 days ‐ immediate treatment | RR 0.81 [0.74, 0.89] | 6 studies · 82624 participants | High |
All‐cause mortality at 10 days‐ short‐term treatment | RR 0.91 [0.86, 0.97] | 6 studies · 78178 participants | High |
Immediate and short term administration of ACE inhibitors in patients with acute cardiovascular events
Population: acute myocardial infarction1
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
All‐cause mortality at 2 days ‐ immediate treatment | RR 0.91 [0.82, 1] | 3 studies · 77414 participants | High |
All‐cause mortality at 10 days ‐ short‐term treatment | RR 0.93 [0.87, 0.98] | 10 studies · 84311 participants | High |
Immediate and short term administration of Beta‐blockers in patients with acute cardiovascular events
Population: patients with acute myocardial infarction1
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
All‐cause mortality at 2 days ‐ immediate treatment | RR 0.95 [0.85, 1.07] | 6 studies · 68007 participants | Low Downgraded: risk of bias |
All‐cause mortality at 10 days ‐ short‐term treatment | RR 0.96 [0.91, 1.02] | 14 studies · 71457 participants | High |
Immediate and short term administration of calcium channel blockers (CCB) in patients with acute cardiovascular events
Population: patients with acute myocardial infarction or stroke1
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
All‐cause mortality at 2 days ‐ immediate treatment | RR 2.33 [0.62, 8.78] | 3 studies · 242 participants | Very low |
All‐cause mortality at 10 days ‐ short‐term treatment | RR 1.01 [0.73, 1.38] | 15 studies · 1900 participants | Very low |