Definite early‐onset neonatal sepsis ‐ Early induction of labour · pregnant women with prelabour rupture of membranes at or near term
Any antibiotic showed no clear difference in definite early‐onset neonatal sepsis ‐ Early induction of labour compared with placebo or no antibiotic (subgrouped by timing of induction of labour) (low certainty).
1 finding from 1 review
Definite early‐onset neonatal sepsis ‐ Late induction of labour · pregnant women with prelabour rupture of membranes at or near term
It is very uncertain whether any antibiotic changes definite early‐onset neonatal sepsis ‐ Late induction of labour compared with placebo or no antibiotic (subgrouped by timing of induction of labour) (very low certainty).
1 finding from 1 review
Maternal infectious morbidity (chorioamnionitis and/or endometritis) ‐ Early induction of labour · pregnant women with prelabour rupture of membranes at or near term
Any antibiotic showed no clear difference in maternal infectious morbidity (chorioamnionitis and/or endometritis)… compared with placebo or no antibiotic (subgrouped by timing of induction of labour) (low certainty).
1 finding from 1 review
Early neonatal sepsis · women with management of intra‐amniotic infection
It is very uncertain whether intrapartum changes early neonatal sepsis compared with postpartum treatment (very low certainty).
1 finding from 1 review
Intervention not reported
Early neonatal death (0 to 6 days) · pregnant women giving birth
The intervention showed no clear difference in early neonatal death (0 to 6 days) (moderate certainty).
1 finding from 1 review
Pre‐eclampsia · women who are not yet pregnant and women in the early stages of pregnancy
Calcium supplementation showed no clear difference in pre‐eclampsia compared with placebo (maternal outcomes) commencing before or early (low certainty).
1 finding from 1 review
Pre‐eclampsia, or pregnancy loss, or stillbirth (or combination) at any gestational age · women who are not yet pregnant and women in the early stages of pregnancy
Calcium supplementation showed no clear difference in pre‐eclampsia, or pregnancy loss, or stillbirth (or combination) at… compared with placebo (maternal outcomes) commencing before or early (low certainty).
1 finding from 1 review
Severe maternal morbidity and mortality index · women who are not yet pregnant and women in the early stages of pregnancy
Calcium supplementation showed no clear difference in severe maternal morbidity and mortality index compared with placebo (maternal outcomes) commencing before or early (low certainty).
1 finding from 1 review
Pregnancy loss or stillbirth at any gestational age · women who are not yet pregnant and women in the early stages of pregnancy
Calcium supplementation showed no clear difference in pregnancy loss or stillbirth at any gestational age compared with placebo (maternal outcomes) commencing before or early (low certainty).
1 finding from 1 review
Caesarean section · women who are not yet pregnant and women in the early stages of pregnancy
Calcium supplementation showed no clear difference in caesarean section compared with placebo (maternal outcomes) commencing before or early (low certainty).
1 finding from 1 review
Low birthweight · women who are not yet pregnant and women in the early stages of pregnancy
Calcium showed no clear difference in birthweight < 2500 g compared with placebo (offspring outcomes) commencing before or early (low certainty).
1 finding from 1 review
Apgar score less than 7 at 5 minutes · women who are not yet pregnant and women in the early stages of pregnancy
It is very uncertain whether calcium changes apgar < 7 at 5 minutes compared with placebo (offspring outcomes) commencing before or early (very low certainty).
1 finding from 1 review
Perinatal death, or NICU admission for > 24 hours (or both) · women who are not yet pregnant and women in the early stages of pregnancy
Calcium showed no clear difference in perinatal death, or NICU admission for > 24 hours (or both) compared with placebo (offspring outcomes) commencing before or early (low certainty).
1 finding from 1 review
Pregnancy loss, stillbirth or neonatal death before discharge · women who are not yet pregnant and women in the early stages of pregnancy
Calcium showed no clear difference in pregnancy loss, stillbirth or NND before discharge compared with placebo (offspring outcomes) commencing before or early (low certainty).
1 finding from 1 review
Maternal death · pregnant women at increased risk of VTE during pregnancy and the early postnatal period
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Adverse effects sufficient to stop treatment · pregnant women at increased risk of VTE during pregnancy and the early postnatal period
It is very uncertain whether antenatal (± postnatal) prophylaxis: LMWH changes adverse effects sufficient to stop treatment compared with UFH (very low certainty).
1 finding from 1 review
Symptomatic thromboembolic events ( · pregnant women at increased risk of VTE during pregnancy and the early postnatal period
It is very uncertain whether antenatal (± postnatal) prophylaxis: heparin (LMWH or UFH) changes symptomatic thromboembolic events ( compared with no treatment/placebo (very low certainty).
1 finding from 1 review
Maternal death · women at increased risk of VTE in the early postpartum period
1 finding from 1 review
Symptomatic thromboembolic events ( · women at increased risk of VTE in the early postpartum period
1 finding from 1 review
Symptomatic PE · women at increased risk of VTE in the early postpartum period
1 finding from 1 review