Calcium supplementation/fortification vs placebo (outcomes: Pre‐eclampsia, or pregnancy loss, or stillbirth (or combination) at any gestational age
- Population
- women who are not yet pregnant and women in the early stages of pregnancy
- Intervention
- Calcium supplementation/fortification
- Comparison
- placebo (outcomes
- Outcome
- Pre‐eclampsia, or pregnancy loss, or stillbirth (or combination) at any gestational age
Calcium supplementation showed no clear difference in pre‐eclampsia, or pregnancy loss, or stillbirth (or combination) at… compared with placebo (maternal outcomes) commencing before or early (low certainty).
What each review found
Include earlier review versions| Finding | Effect | Studies | GRADE certainty |
|---|---|---|---|
Calcium supplementation vs placebo (maternal outcomes) commencing before or early Pre‐eclampsia, or pregnancy loss, or stillbirth (or combination) at any gestational age · women who are not yet pregnant and women in the early stages of pregnancy Calcium supplementation showed no clear difference in pre‐eclampsia, or pregnancy loss, or stillbirth (or combination) at… compared with placebo (maternal outcomes) commencing before or early (low certainty). Calcium supplementation commencing before or early in pregnancy, for preventing hypertensive disorders of… (2019) · Cochrane Headline outcomes only | RR 0.82 [0.66, 1] | 1 study · 633 participants | Low |
Findings are shown side by side, never pooled across reviews.
The reviews
| Review | Searched up to | Included studies | AMSTAR 2 |
|---|---|---|---|
| Calcium supplementation commencing before or early in pregnancy, for preventing hypertensive disorders of pregnancy 2019 · Cochrane Headline outcomes only | Not reported | Not extracted | Not assessed |
How reviews are matched to this question
Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.