Intervention not reported
Risk of VAP within 10 days of intubation in participants intubated for ≥ 24 hours · People who are mechanically ventilated
The intervention may leads to lower risk of VAP within 10 days of intubation in participants intubated… (low certainty).
1 finding from 1 review
Duration of ICU stay · patients with endotracheal intubation in critically ill patients
1 finding from 1 review
Length of hospital stay · patients with endotracheal intubation in critically ill patients
1 finding from 1 review
Duration of mechanical ventilation · patients with endotracheal intubation in critically ill patients
1 finding from 1 review
ICU or LWU length of stay (days) · patients on weaning from mechanical ventilation in adults.
1 finding from 1 review
Intervention not reported
ICU length of stay (days) · mechanically ventilated adult patients
1 finding from 1 review
Duration of mechanical ventilation · Critically ill adults receiving mechanical ventilation in ICU
Daily sedation interruption showed no clear difference in total duration of mechanical ventilation (days) compared with usual care or protocolized sedation strategies that do not include… (moderate certainty).
1 finding from 1 review
Duration of ICU stay · Critically ill adults receiving mechanical ventilation in ICU
Daily sedation interruption showed no clear difference in ICU length of stay (days) compared with usual care or protocolized sedation strategies that do not include… (moderate certainty).
1 finding from 1 review
Length of hospital stay · Critically ill adults receiving mechanical ventilation in ICU
Daily sedation interruption showed no clear difference in hospital length of stay (days) compared with usual care or protocolized sedation strategies that do not include… (moderate certainty).
1 finding from 1 review
Intervention not reported
ICU length of stay (days) · critically ill adults and children requiring weaning from mechanical ventilation
The intervention showed no clear difference in ICU length of stay (days) (moderate certainty).
1 finding from 1 review
Intervention not reported
Hospital length of stay (days) · critically ill adults and children requiring weaning from mechanical ventilation
The intervention showed no clear difference in hospital length of stay (days) (high certainty).
1 finding from 1 review
Intervention not reported
Mortality (ICU, hospital) (days) · critically ill adults and children requiring weaning from mechanical ventilation
The intervention showed no clear difference in mortality (ICU, hospital) (days) (high certainty).
1 finding from 1 review
Duration of mechanical ventilation · critically ill patients or receiving major surgery
1 finding from 1 review
Intervention not reported
Number of days free of mechanical ventilation in a 28 d period · mechanically ventilated participants with acute lung injury and acute respiratory distress syndrome
1 finding from 1 review
Intervention not reported
Duration of mechanical ventilation Measured as number of days · mechanically ventilated adults with need for aerosol bronchodilator therapy
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
28‐Day all‐cause mortality (adult and paediatric patients) · patients with severe sepsis or septic shock
Human recombinant activated protein C showed no clear difference in 28‐Day all‐cause mortality (adult and paediatric patients) compared with placebo (moderate certainty).
1 finding from 1 review
Serious bleeding events in adult and paediatric patients (days 0 to 28) · patients with severe sepsis or septic shock
Human recombinant activated protein C probably leads to higher serious bleeding events in adult and paediatric patients (days 0 to… compared with placebo (moderate certainty).
1 finding from 1 review
Intervention not reported
Mortality 30‐day · Adult patients with SIRS or sepsis
The intervention showed no clear difference in mortality 30‐day (moderate certainty).
1 finding from 1 review
Intervention not reported
Length of stay on the intensive care unit (days) · Adult patients with SIRS or sepsis
1 finding from 1 review
Intervention not reported
Duration of mechanical ventilation (days) · Adult patients with SIRS or sepsis
1 finding from 1 review