Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

1,247 questions · 1,321 findings · 334 reviews

No studies found 73 · 5.5%GRADE not reported 31 · 2.3%Very low 500 · 37.9%Low 406 · 30.7%Moderate 247 · 18.7%High 64 · 4.8%

Evidence‐based psychological interventions vs any comparator

Evidence‐based psychological interventions versus any comparator (Universal programmes) ‐ self‐rated depression scores (higher score is equivalent to a poorer outcome) · Children or adolescents
1 finding from 1 review

Summary of findings: figure‐of‐eight bandage vs arm sling

Shoulder function · patients (mainly young male adults) with fractures of the middle third of the clavicle

It is very uncertain whether summary of findings: figure‐of‐eight bandage changes shoulder function Constant score (0 to 100 points: higher = better) compared with arm sling (very low certainty).

1 finding from 1 review

Statins vs placebo

Valve area (cm2) Better indicated by higher scores. · patients with aortic valve stenosis

Statin showed no clear difference in valve area (cm2) Better indicated by higher scores. compared with placebo (low certainty).

1 finding from 1 review

Bioabsorbable vs metallic interference screws

Functional ability · Adults undergoing surgical reconstruction of a ruptured ACL1
3 findings from 1 review

Bioabsorbable vs metallic interference screws

Activity level: Tegner score ( 0 to 10; higher scores = greater activity) · Adults undergoing surgical reconstruction of a ruptured ACL1
2 findings from 1 review

Mosaicplasty vs microfracture

Function (all scores/instruments): intermediate term IKDC 2000 (version) score. Scale from: 0 to 100; higher scores = better function. · Adults with isolated cartilage defects (defect areas 1.0 cm2 to 6.0 cm2) of the knee

It is very uncertain whether mosaicplasty changes function (all scores/instruments): intermediate term IKDC 2000… compared with microfracture (very low certainty).

1 finding from 1 review

Mosaicplasty vs microfracture

Function (all scores/instruments): long term Scale from: 0 to 100; higher scores = better function. · Adults with isolated cartilage defects (defect areas 1.0 cm2 to 6.0 cm2) of the knee

It is very uncertain whether mosaicplasty changes function (all scores/instruments): long term Scale from: 0 to 100;… compared with microfracture (very low certainty).

1 finding from 1 review

Mosaicplasty vs microfracture

QoL · Adults with isolated cartilage defects (defect areas 1.0 cm2 to 6.0 cm2) of the knee

It is very uncertain whether mosaicplasty changes quality of life: long‐term KOOS QOL score. Scale 0 to 100; higher… compared with microfracture (very low certainty).

1 finding from 1 review

Mosaicplasty vs microfracture

Pain North Americal Spine Society pain scores. Scale from: 0 to 100 (higher scores indicate less pain). · Adults with isolated cartilage defects (defect areas 1.0 cm2 to 6.0 cm2) of the knee

It is very uncertain whether mosaicplasty changes pain: long‐term KOOS Pain score. Scale 0 to 100; higher scores =… compared with microfracture (very low certainty).

1 finding from 1 review

Intervention not reported

Self‐perceived QoL (change from baseline) measured using Peds QL 4.0 Generic Core Scales, scoring 0‐100 points, higher score indicates better quality of life) · children with chronic constipation
1 finding from 1 review