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Evidence found and GRADE certainty

3,097 questions · 3,266 findings · 631 reviews

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No studies found 430 · 13.2%GRADE not reported 193 · 5.9%Very low 995 · 30.5%Low 904 · 27.7%Moderate 591 · 18.1%High 153 · 4.7%

Intervention not reported

Finding 13. The enabling role of trained, multidisciplinary professionals was highlighted. Having the right health and social care professionals can deliver a holistic approach to care. Trained mental health professionals involved in physical acti... · s where they do not wish or feel the need to participate in physical activity.
1 finding from 1 review

LipiFlow vs basic warm compresses

Mean change from baseline in meibomian gland expression scores at 1 to 4 weeks (higher is favored) · people with dry eye

It is very uncertain whether lipiFlow changes mean change from baseline in meibomian gland expression scores at 1… compared with basic warm compresses (very low certainty).

1 finding from 1 review

LipiFlow vs basic warm compresses

Mean change from baseline in meibum quality scores at 1 to 4 weeks (higher is favored) · people with dry eye

It is very uncertain whether lipiFlow changes mean change from baseline in meibum quality scores at 1 to 4 weeks… compared with basic warm compresses (very low certainty).

1 finding from 1 review

LipiFlow vs thermostatic devices

Mean change from baseline in meibomian gland expression scores at 1 to 4 weeks (higher is favored) · people with dry eye

LipiFlow showed no clear difference in mean change from baseline in meibomian gland expression scores at 1… compared with thermostatic devices (low certainty).

1 finding from 1 review

LipiFlow vs thermostatic devices

Mean change from baseline in meibum quality scores at 1 to 4 weeks (higher is favored) · people with dry eye

LipiFlow showed no clear difference in mean change from baseline in meibum quality scores at 1 to 4 weeks… compared with thermostatic devices (low certainty).

1 finding from 1 review

Face‐down positioning vs other positioning

Quality of life assessments at 3 months or later (higher is favored) · people with primary macula‐involving rhegmatogenous retinal detachments

It is very uncertain whether face‐down positioning changes quality of life assessments at 3 months or later (higher is favored) compared with other positioning (very low certainty).

1 finding from 1 review

Serenoa repens vs placebo or no intervention

Urologic symptom scores · men with lower urinary tract symptoms secondary to benign prostatic obstruction

Serenoa repens showed no clear difference in urologic symptom scoreMeasured by IPSS scores (range 0 to 35)Higher… compared with placebo or no intervention (high certainty).

1 finding from 1 review

Serenoa repens in combination with other phytotherapy vs placebo or no intervention

Urologic symptom scores · men with lower urinary tract symptoms secondary to benign prostatic obstruction

Serenoa repens in combination with other phytotherapy showed no clear difference in urologic symptom scoreMeasured by IPSS scores (range 0 to 35)Higher… compared with placebo or no intervention (low certainty).

1 finding from 1 review

Prednisone vs placebo or supportive treatment

Any continuing kidney disease at 3 months (study with high risk of bias excluded) · patients with IgAV

Prednisone showed no clear difference in any continuing kidney disease at 3 months (study with high risk of… compared with placebo or supportive treatment (high certainty).

1 finding from 1 review

Prednisone vs placebo or supportive treatment

Any continuing kidney disease at 12 months (study with high risk of bias excluded) · patients with IgAV

Prednisone showed no clear difference in any continuing kidney disease at 12 months (study with high risk of… compared with placebo or supportive treatment (moderate certainty).

1 finding from 1 review