Findings

What do systematic reviews say?

1,679 questions · 1,720 findings · 335 reviews · Headline outcomes only

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No studies found 192 · 11.2%GRADE not reported 75 · 4.4%Very low 526 · 30.6%Low 504 · 29.3%Moderate 305 · 17.7%High 118 · 6.9%

Acupuncture vs STANDARD DOSE ANTIPSYCHOTICS

Behaviour: Leaving the study early (short‐term) · patients with schizophrenia

1 finding from 1 review

Acupuncture for schizophrenia 2014 · Cochrane Headline outcomes only
no estimate extracted
6 studies · 421 participants
Low

ACUPUNCTURE added to TCM DRUG vs TCM DRUG

Behaviour: Leaving the study early (short‐term) · patients with schizophrenia

1 finding from 1 review

Acupuncture for schizophrenia 2014 · Cochrane Headline outcomes only
no estimate extracted
3 studies · 454 participants
Low

ACUPUNCTURE added to STANDARD DOSE ANTIPSYCHOTICS vs STANDARD DOSE ANTIPSYCHOTICS

Behaviour: Leaving the study early (short‐term) · patients with schizophrenia

It is very uncertain whether ACUPUNCTURE added to STANDARD DOSE ANTIPSYCHOTICS changes behaviour: Leaving the study early (short‐term) compared with STANDARD DOSE ANTIPSYCHOTICS (very low certainty).

1 finding from 1 review

Acupuncture for schizophrenia 2014 · Cochrane Headline outcomes only
RR 1.33 [0.33, 5.45]
10 studies · 870 participants
Very low

Acupuncture vs TCM DRUG

Behaviour: Leaving the study early (short‐term) · patients with schizophrenia

1 finding from 1 review

Acupuncture for schizophrenia 2014 · Cochrane Headline outcomes only
no estimate extracted
3 studies · 328 participants
GRADE not reported

ELECTRIC ACUPUNCTURE CONVULSIVE THERAPY vs ECT

Behaviour: Leaving the study early (short‐term) · patients with schizophrenia

1 finding from 1 review

Acupuncture for schizophrenia 2014 · Cochrane Headline outcomes only
no estimate extracted
1 study · 68 participants
Low

COMPARISON 1. ARIPIPRAZOLE vs QUETIAPINE

Leaving the study early · patients with schizophrenia

It is very uncertain whether COMPARISON 2. ARIPIPRAZOLE changes leaving the study early compared with QUETIAPINE (very low certainty).

1 finding from 1 review

Aripiprazole versus other atypical antipsychotics for schizophrenia 2014 · Cochrane Headline outcomes only
RR 0.8 [0.22, 2.87]
2 studies · 168 participants
Very low

COMPARISON 1. ARIPIPRAZOLE vs RISPERIDONE

Leaving the study early · patients with schizophrenia

It is very uncertain whether COMPARISON 3. ARIPIPRAZOLE changes leaving the study early compared with RISPERIDONE (very low certainty).

1 finding from 1 review

Aripiprazole versus other atypical antipsychotics for schizophrenia 2014 · Cochrane Headline outcomes only
RR 1.02 [0.79, 1.32]
12 studies · 1239 participants
Very low

COMPARISON 1. ARIPIPRAZOLE vs ZIPRASIDONE

Leaving the study early · patients with schizophrenia

It is very uncertain whether COMPARISON 4. ARIPIPRAZOLE changes leaving the study early compared with ZIPRASIDONE (very low certainty).

1 finding from 1 review

Aripiprazole versus other atypical antipsychotics for schizophrenia 2014 · Cochrane Headline outcomes only
RR 0.94 [0.66, 1.34]
2 studies · 316 participants
Very low

COMPARISON 1. ARIPIPRAZOLE vs CLOZAPINE

Leaving the study early · patients with schizophrenia

It is very uncertain whether COMPARISON 1. ARIPIPRAZOLE changes leaving the study early ‐ Any reason compared with CLOZAPINE (very low certainty).

1 finding from 1 review

Aripiprazole versus other atypical antipsychotics for schizophrenia 2014 · Cochrane Headline outcomes only
RR 1.41 [0.46, 4.29]
3 studies · 240 participants
Very low

COMPARISON 1. ARIPIPRAZOLE vs OLANZAPINE

Leaving the study early · patients with schizophrenia

COMPARISON 5. ARIPIPRAZOLE may leads to higher leaving the study early compared with OLANZAPINE (low certainty).

1 finding from 1 review

Aripiprazole versus other atypical antipsychotics for schizophrenia 2014 · Cochrane Headline outcomes only
RR 1.15 [1.05, 1.25]
9 studies · 2331 participants
Low

Pericyazine vs atypical antipsychotics

Leaving the study early for specific reasons · patients with schizophrenia

It is very uncertain whether pericyazine changes leaving the study early for specific reasons compared with atypical antipsychotic (very low certainty).

1 finding from 1 review

Pericyazine for schizophrenia 2014 · Cochrane Headline outcomes only
RR 0.46 [0.11, 1.9]
1 study · 93 participants
Very low

Pericyazine vs Typical antipsychotics

Leaving the study early for specific reasons · patients with schizophrenia

It is very uncertain whether pericyazine changes leaving the study early for specific reasons compared with typical antipsychotic (very low certainty).

1 finding from 1 review

Pericyazine for schizophrenia 2014 · Cochrane Headline outcomes only
RR 0.46 [0.11, 1.9]
2 studies · 71 participants
Very low

Computer‐assisted reconstruction surgery vs conventional operating techniques

IKDC knee examination grade normal (grade A) or nearly normal (grade B) ‐ Intermediate/long‐term · People, primarily adults, undergoing ACL reconstruction surgery

Computer‐assisted reconstruction surgery showed no clear difference in IKDC knee examination grade normal (grade A) or nearly normal (grade… compared with conventional operating techniques (low certainty).

1 finding from 1 review

Computer‐assisted surgery for knee ligament reconstruction 2014 · Cochrane Headline outcomes only
RR 1.01 [0.96, 1.06]
3 studies · 173 participants
Low

Health education vs HEALTH EMPOWERMENT EDUCATION

Leaving the study early · people with serious mental illness

HEALTH EDUCATION showed no clear difference in leaving the study early compared with HEALTH EMPOWERMENT EDUCATION (low certainty).

1 finding from 1 review

General physical health advice for people with serious mental illness 2014 · Cochrane Headline outcomes only
RR 0.56 [0.26, 1.19]
1 study · 78 participants
Low

HEALTHY LIVING STUDY CIRCLE vs AESTHETIC STUDY CIRCLE

Leaving the study early · people with severe mental disorders

HEALTHY LIVING STUDY CIRCLE led to lower leaving the study early compared with AESTHETIC STUDY CIRCLE; GRADE not reported.

1 finding from 1 review

General physical health advice for people with serious mental illness 2014 · Cochrane Headline outcomes only
RR 0 [0, 0]
0 studies · 0 participants
GRADE not reported

PHYSICAL HEALTH ADVICE vs usual care

Leaving the study early · people with severe mental disorders

It is very uncertain whether PHYSICAL HEALTH ADVICE changes leaving the study early compared with STANDARD CARE (very low certainty).

1 finding from 1 review

General physical health advice for people with serious mental illness 2014 · Cochrane Headline outcomes only
RR 1.11 [0.92, 1.35]
6 studies · 964 participants
Very low

Intervention not reported

Symptom Level: Social Interaction Various measures, including: Autism Diagnostic Observation Schedule (ADOS) Communication and Symbolic Behaviour Scale (CSBS) Early Social Communication Scales (ESCS) PDD‐BI social approach subscale Precursors of J... · People with autism spectrum disorder

1 finding from 1 review

Interventions based on the Theory of Mind cognitive model for autism spectrum disorder (ASD) 2014 · Cochrane Headline outcomes only
no estimate extracted
17 participants
Low

Intervention not reported

General Communication Ability (e.g. vocabulary) Mullen Scales of Early Learning (MSEL) Reynell Developmental Language Scales · People with autism spectrum disorder

1 finding from 1 review

Interventions based on the Theory of Mind cognitive model for autism spectrum disorder (ASD) 2014 · Cochrane Headline outcomes only
no estimate extracted
71 participants
Very low

FLUPENTHIXOL vs LOW‐POTENCY ANTIPSYCHOTIC DRUGS

Acceptability of treatment ‐ leaving the study early · patients with schizophrenia

1 finding from 1 review

Flupenthixol versus low‐potency first‐generation antipsychotic drugs for schizophrenia 2014 · Cochrane Headline outcomes only
no estimate extracted
0 studies · 0 participants
GRADE not reported

FLUPHENAZINE vs LOW‐POTENCY ANTIPSYCHOTIC DRUGS

Acceptability of treatment ‐ leaving the study early · patients with schizophrenia

FLUPHENAZINE showed no clear difference in acceptability of treatment‐leaving the study early due to any reason compared with LOW‐POTENCY ANTIPSYCHOTIC DRUGS (moderate certainty).

1 finding from 1 review

Fluphenazine versus low‐potency first‐generation antipsychotic drugs for schizophrenia 2014 · Cochrane Headline outcomes only
RR 1 [0.88, 1.14]
6 studies · 1532 participants
Moderate