Findings

What do systematic reviews say?

3,696 questions · 3,815 findings · 855 reviews

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No studies found 573 · 15%GRADE not reported 374 · 9.8%Very low 993 · 26%Low 1,062 · 27.8%Moderate 614 · 16.1%High 199 · 5.2%

Nebulised hypertonic saline vs nebulised 0.9% saline

Number of days to resolution of symptoms and signs (cough) · infants up to 24 months of age with acute bronchiolitis

1 finding from 1 review

Nebulised hypertonic saline solution for acute bronchiolitis in infants 2023 · Cochrane Headline outcomes only
no estimate extracted
3 studies · 363 participants
Very low

Nebulised hypertonic saline vs nebulised 0.9% saline

Number of days to resolution of symptoms and signs(pulmonary moist crackles) · infants up to 24 months of age with acute bronchiolitis

1 finding from 1 review

Nebulised hypertonic saline solution for acute bronchiolitis in infants 2023 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 205 participants
Very low

ESWL vs RIRS

Duration of hospital stay MCID: 1 day absolute difference · people (>14 years) with kidney stones

1 finding from 1 review

Extracorporeal shock wave lithotripsy (ESWL) versus percutaneous nephrolithotomy (PCNL) or retrograde intrarenal… 2023 · Cochrane Headline outcomes only
no estimate extracted
3 studies · 591 participants
Moderate

ESWL vs PCNL

Duration of hospital stay MCID: 1 day absolute difference · people (>14 years) with kidney stones

1 finding from 1 review

Extracorporeal shock wave lithotripsy (ESWL) versus percutaneous nephrolithotomy (PCNL) or retrograde intrarenal… 2023 · Cochrane Headline outcomes only
no estimate extracted
6 studies · 841 participants
Moderate

Intervention not reported

Length of ICU stay (days admitted to the ICU unit)

1 finding from 1 review

Perioperative glycaemic control for people with diabetes undergoing surgery 2023 · Cochrane Headline outcomes only
no estimate extracted
11 studies · 1687 participants
Low

Intervention not reported

Length of hospital stay (days admitted to the hospital)

1 finding from 1 review

Perioperative glycaemic control for people with diabetes undergoing surgery 2023 · Cochrane Headline outcomes only
no estimate extracted
12 studies · 1520 participants
Very low

Any cold therapy vs no cold therapy following total knee replacement

Blood lossTime point: mean 48 hours, range 1 to 13 days. Higher blood loss indicates a worse outcome. · people undergoing total knee replacement

1 finding from 1 review

Cryotherapy following total knee replacement 2023 · Cochrane Headline outcomes only
no estimate extracted
12 studies · 956 participants
Low

Any cold therapy vs no cold therapy following total knee replacement

Pain at post‐operative day 2Scale from 0 (best) to 10 (worst). · people undergoing total knee replacement

1 finding from 1 review

Cryotherapy following total knee replacement 2023 · Cochrane Headline outcomes only
no estimate extracted
6 studies · 530 participants
Low

Statins vs placebo

Resumption of menstrual regularity · women with polycystic ovary syndrome not actively trying to conceive

1 finding from 1 review

Statins for women with polycystic ovary syndrome not actively trying to conceive 2023 · Cochrane Headline outcomes only
no estimate extracted
1 study · 37 participants
Very low

Low‐intensity pulsed ultrasound vs control

Return to previous activities ‐ Resumption of work (days) · acute fractures in adults; included studies assessed effects in complete upper limb fractures (distal radius, clavicle, scaphoid,…

1 finding from 1 review

Ultrasound and shockwave therapy for acute fractures in adults 2023 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 370 participants
Low

Low‐intensity pulsed ultrasound vs control

Time to fracture union · acute fractures in adults; included studies assessed effects in complete upper limb fractures (distal radius, clavicle, scaphoid,…

1 finding from 1 review

Ultrasound and shockwave therapy for acute fractures in adults 2023 · Cochrane Headline outcomes only
no estimate extracted
11 studies · 887 participants
Very low

Intervention not reported

Acute GVHD II to IV (90 days) · patients after allogeneic stem cell or bone marrow transplantation

The intervention leads to lower acute GVHD II to IV (90 days) (high certainty).

1 finding from 1 review

Polyclonal anti‐thymocyte globulins for the prophylaxis of graft‐versus‐host disease after allogeneic stem cell or… 2023 · Cochrane Headline outcomes only
RR 0.68 [0.6, 0.79]
10 studies · 1413 participants
High

Immunoglobulin vs placebo

Length of hospitalisation (days) · children with respiratory syncytial virus infection

1 finding from 1 review

Immunoglobulin treatment for hospitalised infants and young children with respiratory syncytial virus infection 2023 · Cochrane Headline outcomes only
no estimate extracted
6 studies · 737 participants
Moderate

Summary of findings: endovenous ablation and compression vs compression alone

Ulcer healing time (measured as days from randomisation and followed‐up to 1 year) · people with venous leg ulcers

Summary of findings: endovenous ablation and compression leads to higher ulcer healing time (measured as days from randomisation and… compared with compression alone (high certainty).

1 finding from 1 review

Endovenous ablation for venous leg ulcers 2023 · Cochrane Headline outcomes only
HR 1.41 [1.36, 1.47]
2 studies · 466 participants
High

Summary of findings: endovenous ablation and compression vs compression alone

The proportion of pressure ulcers healed · people with venous leg ulcers

Summary of findings: endovenous ablation and compression showed no clear difference in proportion of ulcers healed at 90 days (90 days compared with compression alone (moderate certainty).

1 finding from 1 review

Endovenous ablation for venous leg ulcers 2023 · Cochrane Headline outcomes only
RR 1.14 [1, 1.3]
2 studies · 466 participants
Moderate

Summary of findings: endovenous ablation and compression vs compression alone

Time to foot ulcer recurrence · people with venous leg ulcers

1 finding from 1 review

Endovenous ablation for venous leg ulcers 2023 · Cochrane Headline outcomes only
no estimate extracted
1 study · 450 participants
Low

Intervention not reported

Total length of hospital stay (days) · people undergoing pancreaticoduodenectomy

The intervention showed no clear difference in total length of hospital stay (days) (low certainty).

1 finding from 1 review

Fibrin sealants for the prevention of postoperative pancreatic fistula following pancreatic surgery 2023 · Cochrane Headline outcomes only
no estimate extracted
4 studies · 447 participants
Low

Intervention not reported

Total length of hospital stay (days) · people undergoing pancreaticoduodenectomy

1 finding from 1 review

Fibrin sealants for the prevention of postoperative pancreatic fistula following pancreatic surgery 2023 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 351 participants
Low

Intervention not reported

Total length of hospital stay (days) · people undergoing distal pancreatectomy

It is very uncertain whether the intervention changes total length of hospital stay (days) (very low certainty).

1 finding from 1 review

Fibrin sealants for the prevention of postoperative pancreatic fistula following pancreatic surgery 2023 · Cochrane Headline outcomes only
MD 0.99
2 studies · 371 participants
Very low

Oral stimulation vs usual care

Time (days) to achieve exclusive oral feeding · preterm infants

1 finding from 1 review

Oral stimulation for promoting oral feeding in preterm infants 2023 · Cochrane Headline outcomes only
no estimate extracted
6 studies · 292 participants
Very low