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Search review questions

Each row is one question a systematic review asked: who, what, compared with what, and which outcome, with the effect it found and how certain that is. Words match anywhere in the field.

Limit to evidence status or GRADE (optional)

75,239 questions in 5,342 reviews

current versions
No studies 15,213 · 20.2%Ungraded 10,323 · 13.7%Very low 17,528 · 23.3%Low 17,951 · 23.9%Moderate 11,190 · 14.9%High 3,034 · 4%

Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.

QuestionEffectEvidenceStatus / GRADE
Intervention NR
Diastolic BP (mm Hg)
Home versus in‐centre haemodialysis for people with kidney failure (2024) · Cochrane
MD 1.813 studies · 383 participantsVery low
Intervention NR
All‐cause death
Home versus in‐centre haemodialysis for people with kidney failure (2024) · Cochrane
RR 0.8 [0.67, 0.95]9 studies · 58984 participantsVery low
Intervention NR
Hospitalisation
Home versus in‐centre haemodialysis for people with kidney failure (2024) · Cochrane
no estimate extractedNRNo studies
Intervention NR
All‐cause annual hospitalisation rate (admissions/patient‐year)
Home versus in‐centre haemodialysis for people with kidney failure (2024) · Cochrane
no estimate extracted2 studies · 834 participantsVery low
Intervention NR
All‐cause annual hospitalisation days (days/patient‐year)
Home versus in‐centre haemodialysis for people with kidney failure (2024) · Cochrane
no estimate extracted2 studies · 834 participantsLow
Intervention NR
Received kidney transplantation
Home versus in‐centre haemodialysis for people with kidney failure (2024) · Cochrane
RR 1.28 [1.01, 1.63]6 studies · 10910 participantsVery low
Intervention NR
Physical Component Summary
Home versus in‐centre haemodialysis for people with kidney failure (2024) · Cochrane
SMD 0.42 [0.1, 0.73]5 studies · 922 participantsVery low
Intervention NR
Mental Component Summary
Home versus in‐centre haemodialysis for people with kidney failure (2024) · Cochrane
SMD 0.15 studies · 922 participantsVery low
Intervention NR
Recovery time (hours)
Home versus in‐centre haemodialysis for people with kidney failure (2024) · Cochrane
no estimate extracted2 studies · 348 participantsLow
Summary of findings table ‐ High‐flow nasal cannula vs standard oxygen therapy (low‐flow)
Length of hospital stay · infants with bronchiolitis
High‐flow nasal cannula therapy for infants with bronchiolitis (2024) · Cochrane
no estimate extracted7 studies · 1951 participantsLow
Summary of findings table ‐ High‐flow nasal cannula vs standard oxygen therapy (low‐flow)
Adverse events · infants with bronchiolitis
High‐flow nasal cannula therapy for infants with bronchiolitis (2024) · Cochrane
RR 1.2 [0.38, 3.74]4 studies · 1789 participantsLow
Summary of findings table ‐ High‐flow nasal cannula vs standard oxygen therapy (low‐flow)
Change in respiratory rate at 4 to 6 hours · infants with bronchiolitis
High‐flow nasal cannula therapy for infants with bronchiolitis (2024) · Cochrane
no estimate extracted5 studies · 692 participantsLow
Summary of findings table ‐ High‐flow nasal cannula vs standard oxygen therapy (low‐flow)
Change in heart rate at 4 to 6 hours · infants with bronchiolitis
High‐flow nasal cannula therapy for infants with bronchiolitis (2024) · Cochrane
no estimate extracted5 studies · 692 participantsModerate
Summary of findings table ‐ High‐flow nasal cannula vs standard oxygen therapy (low‐flow)
Need for treatment escalation · infants with bronchiolitis
High‐flow nasal cannula therapy for infants with bronchiolitis (2024) · Cochrane
RR 0.55 [0.39, 0.79]8 studies · 2215 participantsModerate
Summary of findings table ‐ High‐flow nasal cannula vs standard oxygen therapy (low‐flow)
Duration of oxygen therapy · infants with bronchiolitis
High‐flow nasal cannula therapy for infants with bronchiolitis (2024) · Cochrane
no estimate extracted7 studies · 2132 participantsLow
Microwave coagulation in addition to conventional transarterial chemoembolisation vs conventional transarterial chemoembolisation alone
All‐cause mortality · people with liver metastases
Microwave coagulation for liver metastases (2024) · Cochrane
no estimate extractedNRNo studies
Microwave coagulation vs conventional surgery
Health‐related quality of life · people with liver metastases
Microwave coagulation for liver metastases (2024) · Cochrane
no estimate extractedNRNo studies
Microwave coagulation vs conventional surgery
Any adverse events or complications · people with liver metastases
Microwave coagulation for liver metastases (2024) · Cochrane
no estimate extracted1 study · 30 participantsVery low
Microwave coagulation vs conventional surgery
Disease‐free survival · people with liver metastases
Microwave coagulation for liver metastases (2024) · Cochrane
no estimate extracted1 study · 30 participantsVery low
Microwave coagulation vs conventional surgery
Failure to clear liver metastases · people with liver metastases
Microwave coagulation for liver metastases (2024) · Cochrane
no estimate extractedNRNo studies
Microwave coagulation vs conventional surgery
Recurrence of liver metastases · people with liver metastases
Microwave coagulation for liver metastases (2024) · Cochrane
no estimate extractedNRNo studies
Microwave coagulation vs radiofrequency ablation
All‐cause mortality · people with liver metastases
Microwave coagulation for liver metastases (2024) · Cochrane
RR 0.62 [0.26, 1.47]1 study · 50 participantsVery low
Microwave coagulation vs radiofrequency ablation
Time to mortality (overall survival) · people with liver metastases
Microwave coagulation for liver metastases (2024) · Cochrane
HR 0.63 [0.23, 1.73]1 study · 50 participantsVery low
Microwave coagulation vs radiofrequency ablation
Health‐related quality of life · people with liver metastases
Microwave coagulation for liver metastases (2024) · Cochrane
no estimate extractedNRNo studies
Microwave coagulation vs radiofrequency ablation
Any adverse events or complications · people with liver metastases
Microwave coagulation for liver metastases (2024) · Cochrane
RR 0.19 [0.01, 3.67]1 study · 50 participantsVery low
Microwave coagulation vs radiofrequency ablation
Disease‐free survival · people with liver metastases
Microwave coagulation for liver metastases (2024) · Cochrane
no estimate extractedNRNo studies
Microwave coagulation in addition to conventional transarterial chemoembolisation vs conventional transarterial chemoembolisation alone
Time to mortality · people with liver metastases
Microwave coagulation for liver metastases (2024) · Cochrane
no estimate extractedNRNo studies
Microwave coagulation vs radiofrequency ablation
Failure to clear liver metastases · people with liver metastases
Microwave coagulation for liver metastases (2024) · Cochrane
no estimate extracted1 study · 50 participantsUngraded
Microwave coagulation vs radiofrequency ablation
Recurrence of liver metastases local progression · people with liver metastases
Microwave coagulation for liver metastases (2024) · Cochrane
RR 0.19 [0.01, 3.67]1 study · 50 participantsVery low
Microwave coagulation vs radiofrequency ablation
Recurrence of liver metastases distant recurrence · people with liver metastases
Microwave coagulation for liver metastases (2024) · Cochrane
RR 1.03 [0.5, 2.08]1 study · 50 participantsVery low
Microwave coagulation in addition to conventional transarterial chemoembolisation vs conventional transarterial chemoembolisation alone
Health‐related quality of life · people with liver metastases
Microwave coagulation for liver metastases (2024) · Cochrane
no estimate extractedNRNo studies
Microwave coagulation in addition to conventional transarterial chemoembolisation vs conventional transarterial chemoembolisation alone
Any adverse events or complications · people with liver metastases
Microwave coagulation for liver metastases (2024) · Cochrane
no estimate extracted1 study · 50 participantsVery low
Microwave coagulation in addition to conventional transarterial chemoembolisation vs conventional transarterial chemoembolisation alone
Disease‐free survival · people with liver metastases
Microwave coagulation for liver metastases (2024) · Cochrane
no estimate extractedNRNo studies
Microwave coagulation in addition to conventional transarterial chemoembolisation vs conventional transarterial chemoembolisation alone
Failure to clear liver metastases · people with liver metastases
Microwave coagulation for liver metastases (2024) · Cochrane
no estimate extractedNRNo studies
Microwave coagulation in addition to conventional transarterial chemoembolisation vs conventional transarterial chemoembolisation alone
Recurrence of liver metastases · people with liver metastases
Microwave coagulation for liver metastases (2024) · Cochrane
no estimate extractedNRNo studies
Microwave coagulation vs conventional surgery
All‐cause mortality · people with liver metastases
Microwave coagulation for liver metastases (2024) · Cochrane
no estimate extracted1 study · 40 participantsUngraded
Microwave coagulation vs conventional surgery
Time to mortality (overall survival) · people with liver metastases
Microwave coagulation for liver metastases (2024) · Cochrane
HR 0.91 [0.39, 2.15]1 study · 30 participantsVery low
Nicotine EC vs NRT
Smoking cessation at 6 months to 1 year · People who smoke
Electronic cigarettes for smoking cessation (2024) · Cochrane
RR 1.59 [1.29, 1.93]7 studies · 2544 participantsHigh
Nicotine EC vs NRT
Adverse events at 4 weeks to 6‐9 months Assessed by self‐report · People who smoke
Electronic cigarettes for smoking cessation (2024) · Cochrane
RR 1.03 [0.91, 1.17]5 studies · 2052 participantsModerate
Nicotine EC vs NRT
Serious adverse events at 4 weeks to 1 year Assessed via self‐report and medical records · People who smoke
Electronic cigarettes for smoking cessation (2024) · Cochrane
RR 1.2 [0.9, 1.6]6 studies · 2411 participantsLow
Nicotine EC vs non‐nicotine EC
Smoking cessation at 6‐12 months · People who smoke cigarettes
Electronic cigarettes for smoking cessation (2024) · Cochrane
RR 1.46 [1.09, 1.96]6 studies · 1613 participantsModerate
Nicotine EC vs non‐nicotine EC
Adverse events at 1 week to 6 months Assessed via self‐report · People who smoke cigarettes
Electronic cigarettes for smoking cessation (2024) · Cochrane
RR 1.01 [0.91, 1.11]5 studies · 840 participantsModerate
Nicotine EC vs non‐nicotine EC
Serious adverse events at 1 week to 1 year Assessed via self‐report and medical records · People who smoke cigarettes
Electronic cigarettes for smoking cessation (2024) · Cochrane
RR 1 [0.56, 1.79]9 studies · 1412 participantsLow
Nicotine EC vs behavioural support only/no support
Smoking cessation at 6 to 12 months Assessed using biochemical validation · People who smoke
Electronic cigarettes for smoking cessation (2024) · Cochrane
RR 1.88 [1.56, 2.25]9 studies · 5024 participantsLow
Nicotine EC vs behavioural support only/no support
Adverse events at 12 weeks to 6 months Assessed via self‐report · People who smoke
Electronic cigarettes for smoking cessation (2024) · Cochrane
RR 1.22 [1.12, 1.32]4 studies · 765 participantsLow
Nicotine EC vs behavioural support only/no support
Serious adverse events at 4 weeks to 8 months Assessed via self‐report and medical records · People who smoke
Electronic cigarettes for smoking cessation (2024) · Cochrane
RR 0.89 [0.59, 1.34]10 studies · 3263 participantsVery low
Summary of findings table ‐ Silicone earplugs vs no earplugs
Cerebral palsy at 18 to 22 months' corrected age · preterm or very low birth weight infants
Noise or sound management in the neonatal intensive care unit for preterm or very low birth weight infants (2024) · Cochrane
RR 3 [0.15, 61.74]1 study · 12 participantsVery low
Summary of findings table ‐ Silicone earplugs vs no earplugs
Mental Developmental Index (Bayley II) at 18 to 22 months' corrected age · preterm or very low birth weight infants
Noise or sound management in the neonatal intensive care unit for preterm or very low birth weight infants (2024) · Cochrane
no estimate extracted1 study · 12 participantsVery low
Summary of findings table ‐ Silicone earplugs vs no earplugs
Normal auditory functioning at discharge · preterm or very low birth weight infants
Noise or sound management in the neonatal intensive care unit for preterm or very low birth weight infants (2024) · Cochrane
RR 1.65 [0.93, 2.94]1 study · 21 participantsVery low
Summary of findings table ‐ Silicone earplugs vs no earplugs
All‐cause mortality during hospital stay · preterm or very low birth weight infants
Noise or sound management in the neonatal intensive care unit for preterm or very low birth weight infants (2024) · Cochrane
RR 2.07 [0.64, 6.7]1 study · 34 participantsVery low