Caries experience (mean DMFT) · Brazilian children/adolescents in permanent dentition (BMI classified by CDC 2000 growth charts)
Overweight may make little or no difference to caries experience (DMFT) in the permanent dentition (very low certainty).
1 finding from 1 review
Intervention not reported
Overall success (composite of clinical and radiographic success)
1 finding from 1 review
Mean number of missing teeth in OC cases vs controls · Adults in case-control studies (oral cancer patients vs healthy controls)
The mean number of missing teeth did not differ significantly between oral cancer patients and controls (SMD 0.59, 95% CI -0.04 to 1.22); ungraded.
1 finding from 1 review
Intervention not reported
Decayed, missing, filled surfaces (DMFS)
The intervention showed no clear difference in decayed, missing, filled surfaces (DMFS); GRADE not reported.
1 finding from 1 review
Intervention not reported
Serum vitamin D (25(OH)D): ECC vs caries-free
The intervention led to lower serum vitamin D (25(OH)D): ECC vs caries-free; GRADE not reported.
1 finding from 1 review
Lactobacillus count (CFU/mL) · Children and/or adolescents (<18 years) without background systemic disease
Probiotics may make little to no difference to Lactobacillus count versus control (MD -0.78 CFU/mL, 95%CI -1.65 to 0.09; very low certainty).
1 finding from 1 review
Early childhood caries (ECC) · Children aged 6 years or younger (preschool children)
Serum 25(OH)D 50–75 nmol/l (vs ≥75 nmol/l) was associated with higher odds of ECC (OR 1.42; ungraded).
1 finding from 1 review
Enamel demineralization (QLF ΔF) · Human enamel specimens under cariogenic challenge (in situ / ex vivo)
Evidence on a synergistic effect of combining CO2 laser with fluoride versus fluoride alone is mixed: one ex-vivo study found combined treatment superior while another found no synergy (ungraded, 2 ex-vivo studies, no pooled estimate).
1 finding from 1 review
Spontaneous space closure · Children and adolescents with maxillary permanent first molar extraction
In the maxilla, M2 Demirjian stages F-G were not associated with a statistically significant difference in space closure odds.
1 finding from 1 review
Ion release · Human teeth with early enamel lesions surrounding orthodontic brackets
No meta-analysis was conducted; most studies reported increased ion release over time, but few reported peak values.
1 finding from 1 review
no estimate extracted
8 studies
GRADE not reported
Spontaneous space closure · Children and adolescents after extraction of a mandibular permanent first molar (before eruption of the second molar)
In the mandible, Demirjian stage E-F vs G-H was not significantly associated with space closure (OR 4.44; not GRADE-rated).
1 finding from 1 review
Dental caries prevalence · Brazilian children/adolescents in permanent dentition (BMI classified by WHO 2006 Z-score)
A meta-analysis of 2 studies (permanent dentition, WHO 2006 Z-score) was rated very low certainty; the pooled effect was not shown in the article.
1 finding from 1 review
Spontaneous space closure · Children and adolescents after extraction of a mandibular permanent first molar (before eruption of the second molar)
In the mandible, earlier Demirjian stage A-D (vs F-H) increases odds of space closure (OR 3.11; low certainty).
1 finding from 1 review
Pattern of dental service utilisation and barriers · Adult residents of slums and non-slum urban settings of LMICs
Dental service use is low, episodic and pain-driven, with widespread self-care and cost/funding barriers; ungraded.
1 finding from 1 review
Utilisation was generally low, episodic and mostly problem/pain-driven (pain-driven visits ~70-99%); widespread self-care/home remedies were used as alternatives to professional care; lack of funds/cost, income, age,…
Studies not reported
GRADE not reported
White spot lesion incidence · Orthodontic patients of any age with fixed braces (new DLs assessed at debond)
The self-etch primer system had higher WSL incidence than the conventional system, with certainty not graded.
1 finding from 1 review
Periodontal disease - SNP-based heritability · Japanese adults (present-study cohort)
SNP-based heritability of periodontal disease was low (h2=0.0519, SE 0.0182); ungraded.
1 finding from 1 review
Biofilm morphological changes · Streptococcus mutans (in vitro cultures and biofilms)
Grape seed extract alters S. mutans biofilm morphology (2 studies; ungraded).
1 finding from 1 review
Dental caries · Children (<18 years) with vs without dental caries
After removing Zhang 2006, the recessive model at BsmI(rs1544410) remained non-significant (OR 0.86); ungraded.
2 findings from 1 review
Frequency of mouth cleaning · Adult residents of slums and non-slum urban settings of LMICs
Twice-daily cleaning (recommended) is uncommon; most clean once, in the morning; ungraded.
1 finding from 1 review
White spot lesion rate and volume · Orthodontic patients of any age with fixed braces (new DLs assessed at debond)
Opal Seal showed no significant difference in WSL rate or volume, with certainty not graded.
1 finding from 1 review
The WSL volume was lower in the Opal Seal group than in the Clearfil and Transbond XT groups, but there was no significant difference among the groups (p > 0.05).
1 study · 15 participants
GRADE not reported