Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

2,973 questions · 3,072 findings · 410 reviews · Headline outcomes only

No studies found 559 · 18.2%GRADE not reported 143 · 4.7%Very low 654 · 21.3%Low 833 · 27.1%Moderate 683 · 22.2%High 200 · 6.5%

Intervention not reported

Impulse control disorders (adverse effect, post‐intervention) · people with Parkinson's disease

The intervention showed no clear difference in impulse control disorders (adverse effect, post‐intervention) (moderate certainty).

1 finding from 1 review

Intervention not reported

Impulse control disorders (adverse effect, post‐intervention) · people with Parkinson's disease

The intervention showed no clear difference in impulse control disorders (adverse effect, post‐intervention) (moderate certainty).

1 finding from 1 review

Intervention not reported

Incidence of pulmonary tuberculosis in children with HIV infection ‐ isoniazid prophylaxis only · children with HIV infection aged 12 years and under

The intervention showed no clear difference in incidence of pulmonary tuberculosis in children with HIV infection ‐… (moderate certainty).

1 finding from 1 review

TCu 220C vs Copper 7

Discontinuation due to expulsion (750 days) · patients with Immediate insertion Post abortion

TCu 220C showed no clear difference in discontinuation due to expulsion (750 days) compared with copper 7 (moderate certainty).

1 finding from 1 review

TCu 220C vs Lippes Loop

Discontinuation due to expulsion (750 days) · patients with Immediate insertion Post abortion

TCu 220C probably leads to lower discontinuation rate due to expulsion (750 days) Tietze‐Potter gross… compared with lippes Loop (moderate certainty).

1 finding from 1 review

Intervention not reported

Positive xenodiagnosis: all populations ‐ RCT data ‐ nitroderivatives Xenodiagnosis · people with chronic asymptomatic Trypanosoma cruzi infection

The intervention leads to lower positive xenodiagnosis: all populations ‐ RCT data ‐… (high certainty).

1 finding from 1 review

Intervention not reported

Mean reduction of antibodies titres: all populations, all tested drugs Mean change of antibodies · people with chronic asymptomatic Trypanosoma cruzi infection
1 finding from 1 review

Intervention not reported

Pulmonary haemorrhage · Patients with dengue‐related shock

It is very uncertain whether the intervention changes pulmonary haemorrhage (very low certainty).

1 finding from 1 review

Primary comparison for continuous passive motion (CPM) vs no CPM

Manipulation under anaesthesia · hospitalised patients who have undergone knee replacement surgery

It is very uncertain whether primary comparison for continuous passive motion (CPM) changes manipulation under anaesthesia Counts of manipulation under… compared with no CPM (very low certainty).

1 finding from 1 review

Intensive insulin therapy vs conventional insulin therapy

Occurrence of CIP/CIM ‐ in the total population randomised · critically ill patients

Intensive insulin therapy may leads to lower occurrence of CIP/CIM ‐ in total population randomised compared with conventional insulin therapy (low certainty).

1 finding from 1 review