Cochrane · systematic review · CD011138
Parenteral fluid regimens for improving functional outcome in people with acute stroke
Visvanathan, A, Dennis, M, Whiteley, W · Cochrane Database of Systematic Reviews · 2015 · Cochrane Library
StrokeAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
9
current version
GRADE rated
9
No studies
0
Included studies
NR
No studies 0 · 0%Ungraded 0 · 0%Very low 1 · 11.1%Low 5 · 55.6%Moderate 3 · 33.3%High 0 · 0%
Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.
Questions and results
Colloids versus crystalloids for improving functional outcome in people with acute stroke
Population: people with acute ischaemic or haemorrhagic stroke
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Death or dependence Colloids vs crystalloids | OR 0.97 [0.79, 1.21] | 5 studies · 1420 participants | Low Downgraded: risk of bias, inconsistency |
Death Colloids vs crystalloids | OR 1.02 [0.82, 1.27] | 12 studies · 2351 participants | Moderate |
Pneumonia Colloids vs crystalloids | OR 0.58 [0.17, 2.01] | 2 studies · 416 participants | Moderate Downgraded: risk of bias |
Cerebral oedema Colloids vs crystalloids | OR 0.2 [0.02, 1.74] | 1 study · 200 participants | Low Downgraded: imprecision |
Pulmonary oedema Colloids vs crystalloids | OR 2.34 [1.28, 4.29] | 3 studies · 730 participants | Low |
0.9% saline versus other fluid for improving functional outcome in people with acute stroke
Population: people with acute ischaemic or haemorrhagic stroke
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Death or dependence 0.9% saline vs other fluid | OR 1.04 [0.82, 1.32] | 3 studies · 1120 participants | Low Downgraded: risk of bias, inconsistency |
Death 0.9% saline vs other fluid | OR 0.87 [0.67, 1.12] | 5 studies · 1760 participants | Low Downgraded: risk of bias, inconsistency |
Pneumonia 0.9% saline vs other fluid | OR 2 [0.36, 11.16] | 1 study · 216 participants | Very low Downgraded: risk of bias, imprecision |
Pulmonary oedema 0.9% saline vs other fluid | OR 0.32 [0.14, 0.69] | 1 study · 424 participants | Moderate |