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Evidence found and GRADE certainty

4,534 questions · 5,247 findings · 456 reviews

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No studies found 1,142 · 21.8%GRADE not reported 1,503 · 28.6%Very low 1,040 · 19.8%Low 869 · 16.6%Moderate 554 · 10.6%High 139 · 2.6%

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Diode laser, near infrared (850 nm to 980 nm) vs Placebo (placebo laser or placebo agent) or no treatment

Changes in intensity of pain (VAS 0 to 10) tested through tactile stimuli · Patients aged above 12 years with self-reported tooth hypersensitivity confirmed on clinical evaluation

Diode laser, near infrared (850 nm to 980 nm) led to lower changes in intensity of pain (VAS 0 to 10) tested through tactile… compared with placebo (placebo laser or placebo agent) or no treatment; GRADE not reported.

2 findings from 1 review

In-office laser therapy (all types combined) vs Placebo (placebo laser or placebo agent) or no treatment

Changes in intensity of pain (VAS 0 to 10) tested through tactile stimuli · Patients aged above 12 years with self-reported tooth hypersensitivity confirmed on clinical evaluation

It is very uncertain whether in-office laser therapy (all types combined) changes changes in intensity of pain (VAS 0 to 10) tested through tactile… compared with placebo (placebo laser or placebo agent) or no treatment (very low certainty).

3 findings from 1 review

Nd:YAG laser vs Placebo (placebo laser or placebo agent) or no treatment

Changes in intensity of pain (VAS 0 to 10) tested through tactile stimuli · Patients aged above 12 years with self-reported tooth hypersensitivity confirmed on clinical evaluation

Nd:YAG laser (neodymium-doped:yttrium-aluminum-garnet) showed no clear difference in changes in intensity of pain (VAS 0 to 10) tested through tactile… compared with placebo (placebo laser or placebo agent) or no treatment; GRADE not reported.

2 findings from 1 review

Mineral trioxide aggregate (MTA) vs Super ethoxybenzoic acid (Super-EBA)

Treatment success rate · Patients needing retrograde filling in root canal therapy (orthograde root canal filling or retreatment not possible; periapical surgery…

Mineral trioxide aggregate (MTA) showed no clear difference in success rate at 4 years compared with super ethoxybenzoic acid (Super-EBA); GRADE not reported.

1 finding from 1 review

Diode laser, near infrared (700 nm to 850 nm) vs Placebo (placebo laser or placebo agent) or no treatment

Changes in intensity of pain (VAS 0 to 10) tested through tactile stimuli · Patients aged above 12 years with self-reported tooth hypersensitivity confirmed on clinical evaluation

Diode laser, near infrared (700 nm to 850 nm) showed no clear difference in changes in intensity of pain (VAS 0 to 10) tested through tactile… compared with placebo (placebo laser or placebo agent) or no treatment; GRADE not reported.

2 findings from 1 review

Er:YAG laser (erbium-doped:yttrium-aluminum-garnet) vs Placebo (placebo laser or placebo agent) or no treatment

Outcome not reported · Patients aged above 12 years with self-reported tooth hypersensitivity confirmed on clinical evaluation

The review found no eligible studies for this question.

1 finding from 1 review
  • Laser therapy for dentinal hypersensitivity 2021 · Cochrane All outcomes
    We did not find any eligible study to evaluate erbium:yttrium-aluminum-garnet (Er:YAG) or carbon dioxide (CO2) laser compared with placebo/no treatment.
    0 studies
    No studies found

Diode laser, visible red (630 nm to 700 nm) vs Placebo (placebo laser or placebo agent) or no treatment

Changes in intensity of pain (VAS 0 to 10) tested through air blast stimuli · Patients aged above 12 years with self-reported tooth hypersensitivity confirmed on clinical evaluation

Diode laser, visible red (630 nm to 700 nm) led to lower changes in intensity of pain (VAS 0 to 10) tested through air blast… compared with placebo (placebo laser or placebo agent) or no treatment; GRADE not reported.

3 findings from 1 review

CO2 laser (carbon dioxide) vs Placebo (placebo laser or placebo agent) or no treatment

Outcome not reported · Patients aged above 12 years with self-reported tooth hypersensitivity confirmed on clinical evaluation

The review found no eligible studies for this question.

1 finding from 1 review
  • Laser therapy for dentinal hypersensitivity 2021 · Cochrane All outcomes
    We did not find any eligible study to evaluate erbium:yttrium-aluminum-garnet (Er:YAG) or carbon dioxide (CO2) laser compared with placebo/no treatment.
    0 studies
    No studies found

Intervention not reported

Self‐controlled case series ‐ MMR vaccine ‐ age from 9 to 23 months · children 9 months to 15 years old

The intervention probably leads to higher self‐controlled case series ‐ MMR vaccine ‐ age from 9 to 23 months (moderate certainty).

1 finding from 1 review

Intervention not reported

Cohort study (rate ratio) ‐ all ages · children 9 months to 15 years old

The intervention showed no clear difference in cohort study (rate ratio) ‐ all ages (low certainty).

1 finding from 1 review

Intervention not reported

Cohort studies (risk ratio) ‐ all ages · children 9 months to 15 years old

The intervention showed no clear difference in cohort studies (risk ratio) ‐ all ages (low certainty).

1 finding from 1 review

Er,Cr:YSGG laser (erbium,chromium:yttrium-scandium-gallium-garnet) vs Placebo (placebo laser or placebo agent) or no treatment

Changes in intensity of pain (VAS 0 to 10) tested through tactile stimuli · Patients aged above 12 years with self-reported tooth hypersensitivity confirmed on clinical evaluation

Er,Cr:YSGG laser (erbium,chromium:yttrium-scandium-gallium-garnet) showed no clear difference in changes in intensity of pain (VAS 0 to 10) tested through tactile… compared with placebo (placebo laser or placebo agent) or no treatment; GRADE not reported.

1 finding from 1 review

Mineral trioxide aggregate (MTA) vs Intermediate restorative material (IRM)

Success rate (radiographically‐assessed healing of cyst healing based on the Neer/Cole rating system) · Patients needing retrograde filling in root canal therapy (orthograde root canal filling or retreatment not possible; periapical surgery…

Mineral trioxide aggregate (MTA) showed no clear difference in success rate at 2 years compared with intermediate restorative material (IRM); GRADE not reported.

1 finding from 1 review