Findings

What do systematic reviews say?

Refine by population, intervention, comparison or outcome
More filters
Evidence found and GRADE certainty

76 questions · 80 findings · 10 reviews

No studies found 8 · 10%GRADE not reported 4 · 5%Very low 33 · 41.3%Low 20 · 25%Moderate 12 · 15%High 3 · 3.8%

Summary of Findings Table ‐ Ibuprofen 300 mg vs paracetamol

At least 50% reduction in pain · health problem or population

It is very uncertain whether summary of Findings Table ‐ Ibuprofen 300 mg changes number of participants with at least 50% pain relief at 4 hours compared with active comparator (acetaminophen) (very low certainty).

2 findings from 1 review

Intravenous diclofenac vs placebo

At least 50% reduction in pain · Adults (mean study ages 25 to 55 years) with acute postoperative pain after dental, mixed minor, abdominal, or orthopedic surgeries

Intravenous diclofenac may leads to higher number of participants with at least 50% pain relief at 4 hours compared with placebo (low certainty).

2 findings from 1 review

Intravenous diclofenac vs NSAIDs

Number of participants using rescue medication over 4 to 6 hours postinterventions · Adults (mean study ages 25 to 55 years) with acute postoperative pain after dental, mixed minor, abdominal, or orthopedic surgeries

It is very uncertain whether intravenous diclofenac changes number of participants using rescue medication over 4 to 6 hours… compared with another NSAID (very low certainty).

1 finding from 1 review

Intravenous diclofenac vs NSAIDs

Number of participants reporting an adverse event · Adults (mean study ages 25 to 55 years) with acute postoperative pain after dental, mixed minor, abdominal, or orthopedic surgeries

Intravenous diclofenac showed no clear difference in number of participants reporting any adverse event compared with another NSAID (low certainty).

1 finding from 1 review

Intravenous diclofenac vs NSAIDs

Number of participants experiencing any serious adverse events · Adults (mean study ages 25 to 55 years) with acute postoperative pain after dental, mixed minor, abdominal, or orthopedic surgeries

Intravenous diclofenac showed no clear difference in number of participants experiencing a serious adverse event compared with another NSAID (low certainty).

1 finding from 1 review

Intravenous diclofenac vs placebo

Number of participants using rescue medication over 4 to 6 hours postinterventions · Adults (mean study ages 25 to 55 years) with acute postoperative pain after dental, mixed minor, abdominal, or orthopedic surgeries

Intravenous diclofenac may leads to lower number of participants using rescue medication over 4 to 6 hours… compared with placebo (low certainty).

1 finding from 1 review

Intravenous diclofenac vs placebo

Number of participants reporting an adverse event · Adults (mean study ages 25 to 55 years) with acute postoperative pain after dental, mixed minor, abdominal, or orthopedic surgeries

Intravenous diclofenac showed no clear difference in number of participants reporting any adverse event compared with placebo (low certainty).

1 finding from 1 review

Intravenous diclofenac vs placebo

Number of participants experiencing any serious adverse events · Adults (mean study ages 25 to 55 years) with acute postoperative pain after dental, mixed minor, abdominal, or orthopedic surgeries

Intravenous diclofenac showed no clear difference in number of participants experiencing a serious adverse event compared with placebo (low certainty).

1 finding from 1 review

Intravenous diclofenac vs NSAIDs

At least 50% reduction in pain · Adults (mean study ages 25 to 55 years) with acute postoperative pain after dental, mixed minor, abdominal, or orthopedic surgeries
2 findings from 1 review