Question · asked by 1 review

Summary of Findings Table ‐ Ibuprofen 300 mg vs paracetamol: At least 50% reduction in pain

Population
health problem or population
Intervention
Summary of Findings Table ‐ Ibuprofen 300 mg
Comparison
paracetamol
Outcome
At least 50% reduction in pain

It is very uncertain whether summary of Findings Table ‐ Ibuprofen 300 mg changes number of participants with at least 50% pain relief at 4 hours compared with active comparator (acetaminophen) (very low certainty).

What each review found

Include earlier review versions
No studies found 0 · 0%GRADE not reported 0 · 0%Very low 2 · 100%Low 0 · 0%Moderate 0 · 0%High 0 · 0%
FindingEffectStudiesGRADE certainty
Summary of Findings Table ‐ Ibuprofen 300 mg vs active comparator (acetaminophen)
Number of participants with at least 50% pain relief at 4 hours · health problem or population
It is very uncertain whether summary of Findings Table ‐ Ibuprofen 300 mg changes number of participants with at least 50% pain relief at 4 hours compared with active comparator (acetaminophen) (very low certainty).
Single‐dose intravenous ibuprofen for acute postoperative pain in adults (2021) · Cochrane Headline outcomes only
RR 0.91 [0.58, 1.43]1 study · 151 participantsVery low
Summary of Findings Table ‐ Ibuprofen 300 mg vs active comparator (acetaminophen)
Number of participants with at least 50% pain relief at 6 hours · health problem or population
It is very uncertain whether summary of Findings Table ‐ Ibuprofen 300 mg changes number of participants with at least 50% pain relief at 6 hours compared with active comparator (acetaminophen) (very low certainty).
Single‐dose intravenous ibuprofen for acute postoperative pain in adults (2021) · Cochrane Headline outcomes only
RR 1.03 [0.64, 1.66]1 study · 151 participantsVery low

Findings are shown side by side, never pooled across reviews.

The reviews

ReviewSearched up toIncluded studiesAMSTAR 2
Single‐dose intravenous ibuprofen for acute postoperative pain in adults
2021 · Cochrane Headline outcomes only
Not reportedNot extractedNot assessed
How reviews are matched to this question

Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.