Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

76 questions · 80 findings · 10 reviews

No studies found 8 · 10%GRADE not reported 4 · 5%Very low 33 · 41.3%Low 20 · 25%Moderate 12 · 15%High 3 · 3.8%

Single‐dose vs 10 days

Persistent bacteriuria and symptoms · children with lower urinary tract infection

It is very uncertain whether single‐dose changes persistent bacteriuria and symptoms compared with conventional 10‐day antibiotic treatment (very low certainty).

1 finding from 1 review

Single‐dose antibiotic vs short duration antibiotics

Recurrent asymptomatic bacteriuria ‐ all trials · patients with asymptomatic bacteriuria during pregnancy

It is very uncertain whether single‐dose antibiotic changes recurrent asymptomatic bacteriuria ‐ all trials compared with short‐course (four‐ to seven‐day) antibiotic (very low certainty).

1 finding from 1 review

Single‐dose antibiotic vs short duration antibiotics

Pyelonephritis ‐ Same antimicrobial agent only4 · patients with asymptomatic bacteriuria during pregnancy

It is very uncertain whether single‐dose antibiotic changes pyelonephritis ‐ Same antimicrobial agent only4 compared with short‐course (four‐ to seven‐day) antibiotic (very low certainty).

1 finding from 1 review

Single‐dose antibiotic vs short duration antibiotics

Low birthweight ‐ Same antimicrobial agent only · patients with asymptomatic bacteriuria during pregnancy

Single‐dose antibiotic leads to higher low birthweight ‐ Same antimicrobial agent only compared with short‐course (four‐ to seven‐day) antibiotic (high certainty).

1 finding from 1 review

Single‐dose antibiotic vs short duration antibiotics

Preterm delivery ‐ Same antimicrobial agent only · patients with asymptomatic bacteriuria during pregnancy

Single‐dose antibiotic showed no clear difference in preterm delivery ‐ Same antimicrobial agent only compared with short‐course (four‐ to seven‐day) antibiotic (moderate certainty).

1 finding from 1 review