Radiological failure · Children with extensive decay involving the dental pulp in primary teeth
It is very uncertain whether total-etching 36% phosphoric acid + acetone-based total-etch adhesive changes radiological failure compared with calcium hydroxide (CH) (very low certainty).
1 finding from 1 review
Clinical failure · Children with extensive decay involving the dental pulp in primary teeth
It is very uncertain whether total-etching 36% phosphoric acid + acetone-based total-etch adhesive changes clinical failure compared with non-rinse conditioner + acetone-based total-etch adhesive (very low certainty).
1 finding from 1 review
Clinical failure · Children with extensive decay involving the dental pulp in primary teeth
It is very uncertain whether total-etching 36% phosphoric acid + acetone-based total-etch adhesive changes clinical failure compared with acetone-based total-etch adhesive (very low certainty).
1 finding from 1 review
Radiological failure · Children with extensive decay involving the dental pulp in primary teeth
It is very uncertain whether total-etching 36% phosphoric acid + acetone-based total-etch adhesive changes radiological failure compared with non-rinse conditioner + acetone-based total-etch adhesive (very low certainty).
1 finding from 1 review
Mineral loss (transversal microradiography) · Enamel/dentin specimens with initial caries lesions (or sound surfaces) in intraoral (in situ) appliances worn by patients
Under remineralizing conditions, nHA produced significantly more remineralization than the negative control (MD 350, 95% CI 179 to 521; very low certainty).
2 findings from 1 review
Overall success (composite of clinical and radiographic success) · Adults (18-45 y) with mature permanent molars, carious exposure and symptomatic irreversible pulpitis
Restricting the lateral extent of partial pulpotomy gives success equivalent to more extensive amputation (97.6% vs 97.5%, p>0.05; ungraded, single trial).
1 finding from 1 review
Postoperative pain and analgesic intake · Adults (18-45 y) with mature permanent molars, carious exposure and symptomatic irreversible pulpitis
Restricted partial pulpotomy causes less early postoperative pain and analgesic use than extended amputation (p<0.05; ungraded, single trial).
1 finding from 1 review
Same RCT (Ramani 2024): restricted PP had significantly lower postoperative pain scores on days 1 and 2 (p<0.05) and required significantly less analgesic intake (p<0.05) than extended PP.
1 study · 96 participants
GRADE not reported
Water samples with fluoride concentration below the acceptable range · Artificially fluoridated public water supply in Brazilian cities (water samples under external control)
In the Northeast Brazilian region, a pooled 79.7% of water samples had fluoride below the acceptable range; ungraded.
2 findings from 1 review
Water samples with fluoride concentration above the acceptable range · Artificially fluoridated public water supply in Brazilian cities (water samples under external control)
In the Southeast Brazilian region, a pooled 11.5% of water samples had fluoride above the acceptable range; ungraded.
2 findings from 1 review
Water samples with fluoride concentration outside the acceptable range · Artificially fluoridated public water supply in Brazilian cities (water samples under external control)
In Brazilian cities using external control, more than half of artificially fluoridated public water supply samples (pooled 56.6%, 95% CI 45.5 to 67.3) had fluoride concentrations outside the acceptable range, with very high heterogeneity (I2=99.5%); ungraded.
3 findings from 1 review
A permanent restorative material or technique (e.g. amalgam; glass ionomer (type I-IV); composite resin (macrofilled, microfilled, hybrid, nanofilled); resin-modified glass ionomer (compomer, giomer); cement/cermet; stainless steel or nickel-chrome crown; pre-fabricated resin/porcelain veneer facing; microabrasion) vs A different permanent restorative material or technique
Outcome not reported · Children and adolescents under 18 years with amelogenesis imperfecta requiring restorative care of anterior teeth, irrespective of…
The review found no eligible studies for this question.
1 finding from 1 review
A permanent restorative material or technique (e.g. amalgam; glass ionomer (type I-IV); composite resin (macrofilled, microfilled, hybrid, nanofilled); resin-modified glass ionomer (compomer, giomer); cement/cermet; stainless steel or nickel-chrome crown; pre-fabricated resin/porcelain veneer facing; microabrasion) vs A different permanent restorative material or technique
Outcome not reported · Children and adolescents under 18 years with amelogenesis imperfecta requiring restorative care of posterior teeth, irrespective of…
The review found no eligible studies for this question.
1 finding from 1 review
Remineralization / reduction in lesion severity (change in QLF, laser fluorescence, or lesion area) · People or specimens with white spot lesions or early caries lesions
The NMA estimated an SMD of -0.78 for P11-4 + fluoride varnish versus CPP-ACP (95% CI -1.33 to -0.28).
1 finding from 1 review
SMD -0.78 [-1.33, -0.24]
Studies not reported
GRADE not reported
Weight gain · Healthy, term-born, normal-birth-weight infants aged 4-24 months (breastfed and/or formula-fed) in Western industrialized countries
Narratively, restrictive NRCF style tended to favor excess weight and coercive/pressuring style tended to favor lower weight (3 of 5 studies each; ungraded).
1 finding from 1 review
Early childhood caries (ECC) · Children aged 0-5 years in North Africa
Pooled ECC prevalence in Tunisia was 38% (95% CI 24-51), significantly lower than Egypt and Sudan.
10 findings from 1 review
Prevalence 38 [24, 51]
4 studies
GRADE not reported
Prevalence 48 [39, 58]
9 studies
GRADE not reported
Prevalence 63 [52, 74]
3 studies
GRADE not reported
Show 7 more findings
Early childhood caries (ECC) · Children aged 0-5 years in North Africa
Paternal tertiary education was associated with lower odds of ECC (OR 0.381).
3 findings from 1 review
OR 0.381 [0.16, 0.91]
1 study
GRADE not reported
OR 0.083 [0.03, 0.21]
1 study
GRADE not reported
OR 0.797 [0.171, 0.650]
1 study
GRADE not reported
Early childhood caries (ECC) · Children aged 0-5 years in North Africa
Brushing twice daily was associated with lower odds of ECC (OR 0.033).
2 findings from 1 review
OR 0.033 [0.004, 0.276]
1 study
GRADE not reported
OR 0.033 [0.004, 0.263]
1 study
GRADE not reported
Early childhood caries (ECC) · Children aged 0-5 years in North Africa
Brushing at the recommended time was associated with lower odds of ECC (OR 0.028).
1 finding from 1 review
OR 0.028 [0.004, 0.223]
1 study
GRADE not reported
Early childhood caries (ECC) · Children aged 0-5 years in North Africa
Caries in the mother's mouth was associated with markedly higher odds of ECC (OR 20.44).
1 finding from 1 review
OR 20.44 [8.37, 49.92]
1 study
GRADE not reported
Early childhood caries (ECC) · Children aged 0-5 years in North Africa
Spoon sharing with household members was associated with higher odds of ECC (OR 8.79).
1 finding from 1 review
OR 8.79 [2.92, 26.51]
1 study
GRADE not reported