What do systematic reviews say?

Lay health worker‐led psychosocial interventions vs enhanced usual care

It is very uncertain whether lay health worker‐led psychosocial interventions changes service utilisation ‐ maternal or child hospitalisations ‐… compared with enhanced usual care (very low certainty).

• Primary‐level worker interventions for the care of people living with mental disorders and distress in low‐ and… 2021 · Cochrane Headline outcomes only
  RR 1.12 [0.6, 2.06]
  2 studies · 850 participants
  Very low

Lay health worker‐led psychosocial interventions vs enhanced usual care

• Primary‐level worker interventions for the care of people living with mental disorders and distress in low‐ and… 2021 · Cochrane Headline outcomes only
  no estimate extracted
  4 studies · 1205 participants
  Low

Summary of findings table ‐ Psychosocial interventions intended primarily to reduce antipsychotic use vs (Optimised) usual care

• Psychosocial interventions for reducing antipsychotic medication in care home residents 2023 · Cochrane Headline outcomes only
  no estimate extracted
  5 studies · 5 participants
  Low

Summary of findings table ‐ Psychosocial interventions intended primarily to reduce antipsychotic use vs (Optimised) usual care

• Psychosocial interventions for reducing antipsychotic medication in care home residents 2023 · Cochrane Headline outcomes only
  no estimate extracted
  3 studies · 3 participants
  High

Summary of findings table ‐ Psychosocial interventions intended primarily to reduce antipsychotic use vs (Optimised) usual care

• Psychosocial interventions for reducing antipsychotic medication in care home residents 2023 · Cochrane Headline outcomes only
  no estimate extracted
  5 studies · 7982 participants
  Low

Summary of findings table ‐ Psychosocial interventions intended primarily to reduce antipsychotic use vs (Optimised) usual care

• Psychosocial interventions for reducing antipsychotic medication in care home residents 2023 · Cochrane Headline outcomes only
  no estimate extracted
  2 studies · 2 participants
  Moderate

Summary of findings table ‐ Psychosocial interventions intended primarily to reduce antipsychotic use vs (Optimised) usual care

• Psychosocial interventions for reducing antipsychotic medication in care home residents 2023 · Cochrane Headline outcomes only
  no estimate extracted
  2 studies · 2 participants
  Low

Intervention not reported

• Non‐pharmacological interventions for fatigue in rheumatoid arthritis 2013 · Cochrane Headline outcomes only
  no estimate extracted
  13 studies · 1556 participants
  Low

Task‐oriented interventions vs no intervention

• Task‐oriented interventions for children with developmental co‐ordination disorder 2017 · Cochrane Headline outcomes only
  no estimate extracted
  3 studies · 126 participants
  Very low

Community professional‐led interventions vs no care

• Primary‐level worker interventions for the care of people living with mental disorders and distress in low‐ and… 2021 · Cochrane Headline outcomes only
  no estimate extracted
  2 studies · 602 participants
  Low

Any intervention to prevent violence (all interventions) vs usual care

• Interventions for preventing or reducing domestic violence against pregnant women 2014 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 191 participants
  Very low

Brief intervention vs brief advice, information, or assessment only

• Psychosocial and pharmacologic interventions to reduce harmful alcohol use in low‐ and middle‐income countries 2023 · Cochrane Headline outcomes only
  no estimate extracted
  17 studies · 3913 participants
  Very low
• Psychosocial and pharmacologic interventions to reduce harmful alcohol use in low‐ and middle‐income countries 2023 · Cochrane Headline outcomes only
  no estimate extracted
  4 studies · 1349 participants
  Very low

Brief intervention vs brief advice, information, or assessment only

• Psychosocial and pharmacologic interventions to reduce harmful alcohol use in low‐ and middle‐income countries 2023 · Cochrane Headline outcomes only
  no estimate extracted
  12 studies · 5380 participants
  Very low

Any Psychosocial intervention plus pharm vs psychosocial interventions

• Psychosocial and pharmacologic interventions to reduce harmful alcohol use in low‐ and middle‐income countries 2023 · Cochrane Headline outcomes only
  no estimate extracted
  4 studies · 475 participants
  Low
• Psychosocial and pharmacologic interventions to reduce harmful alcohol use in low‐ and middle‐income countries 2023 · Cochrane Headline outcomes only
  RR 0.62 [0.16, 2.47]
  1 study · 102 participants
  Very low

Any Psychosocial intervention plus pharm vs psychosocial interventions

Pharmacologic intervention along with psychosocial intervention showed no clear difference in retention compared with psychosocial intervention alone (moderate certainty).

• Psychosocial and pharmacologic interventions to reduce harmful alcohol use in low‐ and middle‐income countries 2023 · Cochrane Headline outcomes only
  RR 1.15 [0.95, 1.4]
  3 studies · 363 participants
  Moderate

Summary of Findings Table ‐ The Lidcombe Program vs waiting list control

• Non‐pharmacological interventions for stuttering in children six years and younger 2021 · Cochrane Headline outcomes only
  no estimate extracted
  0 studies · 0 participants
  GRADE not reported

Other psychosocial intervention vs usual care, brief intervention, or wait list

• Psychosocial and pharmacologic interventions to reduce harmful alcohol use in low‐ and middle‐income countries 2023 · Cochrane Headline outcomes only
  no estimate extracted
  12 studies · 2106 participants
  Very low

Other psychosocial intervention vs usual care, brief intervention, or wait list

• Psychosocial and pharmacologic interventions to reduce harmful alcohol use in low‐ and middle‐income countries 2023 · Cochrane Headline outcomes only
  no estimate extracted
  9 studies · 1664 participants
  Very low

Comparison 7: Other mixed interventions vs treatment

It is very uncertain whether comparison 7: Other mixed interventions changes repetition of SH at 12 months compared with treatment (very low certainty).

• Psychosocial interventions for self‐harm in adults 2016 · Cochrane Headline outcomes only
  OR 0.4 [0.06, 2.57]
  1 study · 33 participants
  Very low

Comparison 7: Other mixed interventions vs treatment

Comparison 7: Other mixed interventions showed no clear difference in repetition of SH at final compared with treatment (low certainty).

• Psychosocial interventions for self‐harm in adults 2016 · Cochrane Headline outcomes only
  OR 1.02 [0.71, 1.47]
  1 study · 1663 participants
  Low
• Psychosocial interventions for self‐harm in adults 2016 · Cochrane Headline outcomes only
  OR 2.27 [0.97, 5.28]
  1 study · 135 participants
  Very low
• Psychosocial interventions for self‐harm in adults 2016 · Cochrane Headline outcomes only
  OR 0.55 [0.13, 2.34]
  1 study · 251 participants
  Very low