Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

127 questions · 135 findings · 22 reviews

No studies found 33 · 24.4%GRADE not reported 19 · 14.1%Very low 45 · 33.3%Low 23 · 17%Moderate 10 · 7.4%High 5 · 3.7%

Intervention not reported

Recurrence of hyperthyroidism (relapse) [measured by serum thyroid hormone levels above the normal range after withdrawal of methimazole or end of radioiodine treatment]

It is very uncertain whether the intervention changes recurrence of hyperthyroidism (relapse) [measured by serum thyroid… (very low certainty).

1 finding from 1 review

Subgingival laser irradiation + povidone-iodine vs SRP

Volatile sulphur compounds (VSC), halimeter · Adolescents and adults aged over 16 years with clinical or self-assessed halitosis of oral origin; excluding induced or physiological…

Subgingival laser irradiation + povidone-iodine led to higher volatile sulphur compounds (VSC) compared with SRP alone; GRADE not reported.

1 finding from 1 review

Subgingival laser irradiation + povidone-iodine vs SRP

Dentist-reported organoleptic test (OLT) score (scale 0 to 5) · Adolescents and adults aged over 16 years with clinical or self-assessed halitosis of oral origin; excluding induced or physiological…

It is very uncertain whether subgingival laser irradiation + povidone-iodine changes dentist-reported organoleptic test (OLT) score (scale 0 to 5) compared with SRP alone (very low certainty).

1 finding from 1 review

Prophylaxis (teeth cleaning) and CHX or iodine-NaF solution application in the dentition of women (mothers) vs placebo

Mother microbiological presence · For interventions, pregnant women and mothers of infants in the first year of life; for outcomes, children up to 6 years of age
1 finding from 1 review

Prophylaxis (teeth cleaning) and CHX or iodine-NaF solution application in the dentition of women (mothers) vs placebo

Adverse events for mother or child · For interventions, pregnant women and mothers of infants in the first year of life; for outcomes, children up to 6 years of age
1 finding from 1 review

Prophylaxis (teeth cleaning) and CHX or iodine-NaF solution application in the dentition of women (mothers) vs placebo

Dental caries · For interventions, pregnant women and mothers of infants in the first year of life; for outcomes, children up to 6 years of age

The review found no eligible studies for this question.

2 findings from 1 review

Prophylaxis (teeth cleaning) and CHX or iodine-NaF solution application in the dentition of women (mothers) vs placebo

Caries presence in primary teeth · For interventions, pregnant women and mothers of infants in the first year of life; for outcomes, children up to 6 years of age

It is very uncertain whether prophylaxis (teeth cleaning) and CHX or iodine-NaF solution… changes caries presence in primary teeth compared with placebo (very low certainty).

1 finding from 1 review

Prophylaxis (teeth cleaning) and CHX or iodine-NaF solution application in the dentition of women (mothers) vs placebo

Child microbiological presence (mutans streptococci acquisition) · For interventions, pregnant women and mothers of infants in the first year of life; for outcomes, children up to 6 years of age
1 finding from 1 review

Prophylaxis (teeth cleaning) and CHX or iodine-NaF solution application in the dentition of women (mothers) vs placebo

Mother caries (DMFT increment) · For interventions, pregnant women and mothers of infants in the first year of life; for outcomes, children up to 6 years of age

Prophylaxis (teeth cleaning) and CHX or iodine-NaF solution… showed no clear difference in mother caries (DMFT increment) compared with placebo; GRADE not reported.

1 finding from 1 review

Prophylaxis (teeth cleaning) and CHX or iodine-NaF solution application in the dentition of women (mothers) vs placebo

Mother caries (dmfs increment) · For interventions, pregnant women and mothers of infants in the first year of life; for outcomes, children up to 6 years of age

Prophylaxis (teeth cleaning) and CHX or iodine-NaF solution… showed no clear difference in mother caries (dmfs increment) compared with placebo; GRADE not reported.

1 finding from 1 review

NMA evidence for individual network: proportion with complete healing ‐ interventions vs saline gauze

Iodine‐containing dressings · people with pressure ulcers

It is very uncertain whether NMA evidence for individual network: proportion with complete… changes iodine‐containing dressings compared with saline gauze (very low certainty).

1 finding from 1 review

Intervention vs any comparison

Mortality ‐ Topical povidone iodine gel versus no topical povidone iodine gel · patients undergoing liver resections

It is very uncertain whether intervention changes mortality ‐ Topical povidone iodine gel versus no topical povidone… compared with comparison (very low certainty).

1 finding from 1 review

Chlorhexidine vs povidone‐iodine

Reduction in level of contamination by particles <=5 um (droplet nuclei) at >=2 m from patient's oral cavity · Dental patients undergoing aerosol-generating procedures (AGPs) and the dental healthcare providers treating them

It is very uncertain whether chlorhexidine (CHX) changes reduction in level of contamination by particles <=5 um (droplet… compared with povidone iodine (very low certainty).

2 findings from 1 review

Chlorhexidine vs povidone‐iodine

Reduction in level of contamination by particles >5 um (droplets) at <2 m from patient's oral cavity · Dental patients undergoing aerosol-generating procedures (AGPs) and the dental healthcare providers treating them

It is very uncertain whether chlorhexidine (CHX) changes reduction in level of contamination by particles >5 um (droplets) at… compared with povidone iodine (very low certainty).

2 findings from 1 review

Hydrogel dressings vs povidone‐iodine

Time to complete healing · adults with open wounds after surgery for sacrococcygeal pilonidal sinus disease

It is very uncertain whether hydrogel dressing changes time to wound healing (days) compared with wound cleaning with 10% povidone iodine (very low certainty).

1 finding from 1 review

Hydrogel dressings vs povidone‐iodine

Proportion of wounds healed · adults with open wounds after surgery for sacrococcygeal pilonidal sinus disease

The review found no eligible studies for this question.

3 findings from 1 review