Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

103 questions · 103 findings · 14 reviews · Anaesthesia

No studies found 15 · 14.6%GRADE not reported 6 · 5.8%Very low 21 · 20.4%Low 24 · 23.3%Moderate 30 · 29.1%High 7 · 6.8%

Thoracic epidural anaesthesia vs conventional pain control

Persistent pain 3 to 18 months after thoracotomy (We defined persistent postsurgical pain as new pain that did not exist before the operation, measured using differences in scores based on validated pain scales; patient interview between 3 to 18 m... · Patients undergoing thoracotomy

Thoracic epidural anaesthesia probably leads to lower persistent pain 3 to 18 months after thoracotomy (We defined… compared with conventional pain control (moderate certainty).

1 finding from 1 review

Epidural anaesthesia in addition to general anaesthesia vs general anaesthesia

Death from all causes Range of · patients undergoing primary tumour surgery

Epidural anaesthesia in addition to general anaesthesia showed no clear difference in death from all causes Range of compared with general anaesthesia alone (low certainty).

1 finding from 1 review

Epidural anaesthesia in addition to general anaesthesia vs general anaesthesia

Tumour progression or death from all causes Range of · patients undergoing primary tumour surgery

It is very uncertain whether epidural anaesthesia in addition to general anaesthesia changes tumour progression or death from all causes Range of compared with general anaesthesia alone (very low certainty).

1 finding from 1 review

Epidural anaesthesia in addition to general anaesthesia vs general anaesthesia

Tumour progression Median · patients undergoing primary tumour surgery

It is very uncertain whether epidural anaesthesia in addition to general anaesthesia changes tumour progression Median compared with general anaesthesia alone (very low certainty).

1 finding from 1 review

Automated mandatory bolus vs basal infusion

Breakthrough pain · term, pregnant women (nulliparous, or combination of nulli‐ and muliparous) requesting for labour epidural analgesia

Automated mandatory bolus probably leads to lower breakthrough pain compared with basal infusion (moderate certainty).

1 finding from 1 review