Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

193 questions · 196 findings · 33 reviews

No studies found 21 · 10.7%GRADE not reported 16 · 8.2%Very low 43 · 21.9%Low 52 · 26.5%Moderate 49 · 25%High 15 · 7.7%

Early initiation of epidural analgesia vs Late initiation

Caesarean section · pregnant women (at term) requesting epidural analgesia in labour (regardless of whether the labour was spontaneous or induced)

Early initiation of epidural analgesia showed no clear difference in caesarean section compared with late initiation (high certainty).

1 finding from 1 review

Early initiation of epidural analgesia vs Late initiation

Instrumental delivery · pregnant women (at term) requesting epidural analgesia in labour (regardless of whether the labour was spontaneous or induced)

Early initiation of epidural analgesia showed no clear difference in instrumental delivery compared with late initiation (high certainty).

1 finding from 1 review

Early initiation of epidural analgesia vs Late initiation

Apgar score less than 7 at 5 minutes · pregnant women (at term) requesting epidural analgesia in labour (regardless of whether the labour was spontaneous or induced)

Early initiation of epidural analgesia showed no clear difference in apgar score <7 at 5 min compared with late initiation (high certainty).

1 finding from 1 review