Cochrane · systematic review · CD011344

Automated mandatory bolus versus basal infusion for maintenance of epidural analgesia in labour

Tan, HS, Zeng, Y, Qi, Y, et al. · Cochrane Database of Systematic Reviews · 2023 · Cochrane Library

Anaesthesia2 versionsAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
7
current version
GRADE rated
5
No studies
0
Included studies
NR
No studies 0 · 0%Ungraded 2 · 28.6%Very low 0 · 0%Low 0 · 0%Moderate 5 · 71.4%High 0 · 0%

Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.

Questions and results

Show all 2 versions

Automated mandatory bolus versus basal infusion for maintenance of epidural analgesia in labour

Population: term, pregnant women (nulliparous, or combination of nulli‐ and muliparous) requesting for labour epidural analgesia
7 questions
OutcomeEffectEvidenceStatus / GRADE
Breakthrough pain
Automated mandatory bolus vs basal infusion
RR 0.71 [0.55, 0.91]16 studies · 1528 participantsModerate
Downgraded: inconsistency
Caesarean delivery during labour epidural analgesia
Automated mandatory bolus vs basal infusion
RR 0.85 [0.69, 1.06]16 studies · 1735 participantsModerate
Downgraded: imprecision, inconsistency
Instrumental delivery during labour epidural analgesia
Automated mandatory bolus vs basal infusion
RR 0.85 [0.71, 1.01]17 studies · 4550 participantsModerate
Downgraded: imprecision, inconsistency
Duration of labour analgesia in minutes
Automated mandatory bolus vs basal infusion
no estimate extracted17 studies · 4544 participantsModerate
Downgraded: imprecision, inconsistency
Local anaesthetic consumption per hour (mg/hr)c during labour epidural analgesia
Automated mandatory bolus vs basal infusion
no estimate extracted16 studies · 1642 participantsModerate
Downgraded: imprecision, inconsistency
Maternal satisfaction following fetal delivery
Automated mandatory bolus vs basal infusion
no estimate extracted14 studies · 14 participantsUngraded
Apgar scores at 1‐ and 5‐minutes following fetal delivery
Automated mandatory bolus vs basal infusion
no estimate extracted14 studies · 14 participantsUngraded